UniProt I7G2R2
Drug exporters of the RND superfamily-like protein (I7G2R2)
Drug exporters of the RND superfamily-like protein (UniProt I7G2R2), EC 3.2.1.17: 20 experimental structures on GenesisL1, 11 ligands bound, 74 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- I7G2R2
- Protein
- Drug exporters of the RND superfamily-like protein
- EC
- 3.2.1.17
- Experimental structures
- 20
- Predicted models
- 0
- Ligands
- 11
- Pockets
- 74 · 7 records with a druggable one
Structures
20 records of I7G2R2 in the MolNFT archive: 20 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6AJF | Crystal structure of mycolic acid transporter MMPL3 from mycobacterium smegmatis | x-ray diffraction | A | MHA, L6T | — |
| 6AJG | Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with… | x-ray diffraction | A | 3RX, MHA | 9 (best 0.81) |
| 6AJG | Crystal structure of mycolic acid transporter MMPL3 from mycobacterium smegmatis complexed with… | x-ray diffraction | A | 3RX, MHA | — |
| 6AJH | Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with… | x-ray diffraction | A | 9ZF, L6T, MHA | 7 (best 0.81) |
| 6AJH | Crystal structure of mycolic acid transporter MMPL3 from mycobacterium smegmatis complexed with… | x-ray diffraction | A | 9ZF, L6T, MHA | — |
| 6AJI | Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with… | x-ray diffraction | A | AY6, L6T, MHA | — |
| 6AJI | Crystal structure of mycolic acid transporter MMPL3 from mycobacterium smegmatis complexed with… | x-ray diffraction | A | AY6, L6T, MHA | — |
| 6AJJ | Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with… | x-ray diffraction | A | MHA, L6T, J9E | 5 (best 0.81) |
| 6AJJ | Crystal structure of mycolic acid transporter MMPL3 from mycobacterium smegmatis complexed with… | x-ray diffraction | A | MHA, L6T, J9E | — |
| 7C2M | Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with… | x-ray diffraction | A | FFU, L6T, MHA | 9 (best 0.82) |
| 7C2M | Crystal structure of mycolic acid transporter MMPL3 from mycobacterium smegmatis complexed with… | x-ray diffraction | A | FFU, L6T, MHA | — |
| 7C2N | Crystal structure of mycolic acid transporter MMPL3 from mycobacterium smegmatis complexed with… | x-ray diffraction | A | L6T, MHA, FG0 | — |
| 7K7M | Crystal Structure of a membrane protein | x-ray diffraction | A, B | U2D, GLC | 14 (best 0.80) |
| 7K7M | Crystal structure of a membrane protein | x-ray diffraction | A, B | U2D, GLC | — |
| 7K8A | CryoEM structure of a trehalose monomycolate transporter in lipid nanodiscs | electron microscopy | A | — | 11 (best 0.82) |
| 7K8A | Cryoem structure of a trehalose monomycolate transporter in lipid nanodiscs | electron microscopy | A | — | — |
| 7K8B | Cryoem structure of a trehalose monomycolate transporter in lipid nanodiscs | electron microscopy | A | — | — |
| 7K8D | CryoEM structure of a trehalose monomycolate transporter in TMM lipid nanodiscs (form II) | electron microscopy | A | — | 19 (best 0.87) |
| 7K8D | Cryoem structure of a trehalose monomycolate transporter in tmm lipid nanodiscs (form II) | electron microscopy | A | — | — |
| 7N6B | Structure of MMPL3 reconstituted into lipid nanodisc in the tmm bound state | electron microscopy | A | 0HJ | — |
Ligands
- MHA · (carbamoylmethyl-carboxymethyl-amino)-acetic acid · in 12 records
- L6T · alpha-D-glucopyranosyl 6-O-dodecyl-alpha-D-glucopyranoside · in 10 records
- 3RX · N-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-N'-[(1R,3S,5R, 7R)-tricyclo[3.3.1.1~3,7~]dec-2-yl]ethane-1,2-diamine · in 2 records
- 9ZF · 1-(2-adamantyl)-3-[2,3,4-tris(fluoranyl)phenyl]urea · in 2 records
- AY6 · 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide · in 2 records
- FFU · N-(4,4-dimethylcyclohexyl)-4,6-bis(fluoranyl)-1H-indole-2-carboxamide · in 2 records
- GLC · alpha-D-glucopyranose · in 2 records
- J9E · 4,6-difluoro-N-(spiro[5.5]undecan-3-yl)-1H-indole-2-carboxamide · in 2 records
- U2D · 6-O-decanoyl-alpha-D-glucopyranose · in 2 records
- 0HJ · 6-O-[(2S)-2-{(1S)-18-[(1R,2R)-2-hexylcyclopropyl]-1-hydroxyoctadecyl}tricosanoyl]-alpha-D-glucopyranosyl alpha-D-glucopyranoside · in 1 record
- FG0 · 1'-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)spiro[6,7-dihydrothieno[3,2-c]pyran-4,4'-piperidine] · in 1 record
Elsewhere
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