MolNFT v1 · #179530 · protein
Cryoem structure of a trehalose monomycolate transporter in tmm lipid nanodiscs (form II)
7K8D · Drug exporters of the rnd superfamily-like protein: “Cryoem structure of a trehalose monomycolate transporter in tmm lipid nanodiscs (form II)”. Electron microscopy, 19 pockets (best druggability 0.87). MolNFT v1 #179530 on…
- PDB
- 7K8D
- Type
- protein
- Length
- 725 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Drug exporters of the rnd superfamily-like protein
- UniProt
- I7G2R2
- Pockets
- 19 · best druggability 0.87
Structure
electron microscopy · 1 distinct chain · 67% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Drug exporters of the rnd superfamily-like protein | protein | 725 | 67% helix, 5% strand | I7G2R2 |
Pockets
19 pockets found on a 1 Å grid, 12 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 670 | 0.87 | 0.91 | 97 | empty |
| 2 | 701 | 0.86 | 0.89 | 77 | empty |
| 3 | 550 | 0.78 | 0.84 | 80 | empty |
| 4 | 122 | 0.76 | 0.95 | 31 | empty |
| 5 | 290 | 0.69 | 0.83 | 41 | empty |
Compared structures
- 7K8D · CryoEM structure of a trehalose monomycolate transporter in TMM lipid nanodiscs (form II) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt I7G2R2
- Elsewhere: RCSB PDB 7K8D · PDBe 7K8D · UniProt I7G2R2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.