UniProt I3LK43
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (I3LK43)
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (UniProt I3LK43): 26 experimental structures on GenesisL1, 8 ligands bound, 27 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- I3LK43
- Protein
- NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial
- Experimental structures
- 26
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 27 · 6 records with a druggable one
Structures
26 records of I3LK43 in the MolNFT archive: 26 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7V2C | Active state complex I from Q10 dataset | electron microscopy | C | SF4, PEE, PLX, NDP, UQ | — |
| 7V2D | Deactive state complex I from Q10 dataset | electron microscopy | C | SF4, PLX, NDP, PEE, UQ | 4 (best 0.86) |
| 7V2D | Deactive state complex I from Q10 dataset | electron microscopy | C | SF4, PLX, NDP, PEE, UQ | — |
| 7V2E | Active state complex I from Q10-NADH dataset | electron microscopy | C | SF4, PEE, PLX, NDP, UQ | — |
| 7V2F | Deactive state complex I from Q10-NADH dataset | electron microscopy | C | SF4, PEE, PLX, NDP, UQ | 5 (best 0.85) |
| 7V2F | Deactive state complex I from Q10-NADH dataset | electron microscopy | C | SF4, PEE, PLX, NDP, UQ | — |
| 7V2H | Active state complex I from dq-NADH dataset | electron microscopy | C | SF4, PEE, PLX, NDP, DCQ, UQ | — |
| 7V2K | Deactive state complex I from DQ-NADH dataset | electron microscopy | C | SF4, PEE, PLX, NDP, UQ | 4 (best 0.88) |
| 7V2K | Deactive state complex I from dq-NADH dataset | electron microscopy | C | SF4, PEE, PLX, NDP, UQ | — |
| 7V2R | Active state complex I from Q1-NADH dataset | electron microscopy | C | SF4, PEE, PLX, UQ, NDP, UQ1 | — |
| 7V30 | Deactive state complex I from Q1-NADH dataset | electron microscopy | C | SF4, PEE, PLX, NDP, UQ | — |
| 7V31 | Active state complex I from rotenone dataset | electron microscopy | C | SF4, PLX, 970, NDP, PEE, UQ | — |
| 7V32 | Deactive state complex I from rotenone dataset | electron microscopy | C | SF4, PLX, NDP, PEE, UQ | — |
| 7V33 | Active state complex I from rotenone-NADH dataset | electron microscopy | C | SF4, PEE, PLX, NDP, 970, UQ | — |
| 7V3M | Deactive state complex I from rote -NADH dataset | electron microscopy | C | SF4, PEE, PLX, NDP, UQ | — |
| 7V3M | Deactive state complex I from rotenone-NADH dataset | electron microscopy | C | SF4, PEE, PLX, NDP, UQ | — |
| 7VB7 | Matrix arm of active state ci from dq-NADH dataset | electron microscopy | C | SF4, PEE, PLX, NDP, DCQ | — |
| 7VBN | Matrix arm of deactive state ci from dq-NADH dataset | electron microscopy | C | SF4, PEE, PLX, NDP | — |
| 7VBZ | Matrix arm of active state ci from rotenone-NADH dataset | electron microscopy | C | SF4, PEE, PLX, NDP, 970 | — |
| 7VWJ | Matrix arm of deactive state CI from rote -NADH dataset | electron microscopy | C | SF4, PEE, PLX, NDP | — |
| 7VWJ | Matrix arm of deactive state ci from rotenone-NADH dataset | electron microscopy | C | SF4, PEE, PLX, NDP | — |
| 7VYF | Matrix arm of active state CI from Rote dataset | electron microscopy | C | SF4, 970, PEE, NDP | — |
| 7W2R | Active state CI from DQ-NADH dataset, Subclass 1 | electron microscopy | C | SF4, PEE, PLX, DCQ, NDP, UQ | 5 (best 0.89) |
| 7W35 | Deactive state CI from DQ-NADH dataset, Subclass 3 | electron microscopy | C | SF4, PLX, NDP, UQ | 4 (best 0.86) |
| 7W4G | Active state CI from Q1-NADH dataset, Subclass 5 | electron microscopy | C | SF4, PEE, PLX, UQ1, NDP, UQ | 5 (best 0.89) |
| 7W4J | Deactive state CI from Q1-NADH dataset, Subclass 1 | electron microscopy | C | SF4, PLX, NDP, PEE, UQ | — |
Ligands
- NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate · in 26 records
- SF4 · Iron/sulfur cluster · in 26 records
- PEE · 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine · in 25 records
- PLX · (9R,11S)-9-({[(1S)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol · in 25 records
- UQ · Coenzyme Q10, (2Z,6E,10Z,14E,18E,22E,26Z)-isomer · in 20 records
- 970 · (2r,6as,12as)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12, 12A-tetrahydrofuro[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-6(6ah)-one · in 4 records
- DCQ · 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione · in 3 records
- UQ1 · Ubiquinone-1 · in 2 records
Elsewhere
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