UniProt H7C560

Non-specific serine/threonine protein kinase (H7C560)

Non-specific serine/threonine protein kinase (UniProt H7C560), EC 2.7.11.1: 3 experimental structures on GenesisL1, 3 ligands bound, 11 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt: H7C560
Protein: Non-specific serine/threonine protein kinase
EC: 2.7.11.1
Experimental structures: 3
Predicted models: 0
Ligands: 3
Pockets: 11 · 1 record with a druggable one

Structures

3 records of H7C560 in the MolNFT archive: 3 experimental, 0 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6XFP	Crystal structure of braf kinase domain bound to belvarafenib	x-ray diffraction	A	V1Y, CL	—
7K0V	Crystal structure of bRaf in complex with inhibitor GNE-0749	x-ray diffraction	A, B, C, D	VQP, CL	11 (best 0.84)
7K0V	Crystal structure of braf in complex with inhibitor gne-0749	x-ray diffraction	A, B, C, D	VQP, CL	—

Ligands

CL · Chloride ion · in 3 records
VQP · N-(3,3-dimethylbutyl)-N'-{2-fluoro-5-[(5-fluoro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]-4-methylphenyl}urea · in 2 records
V1Y · 4-amino-N-{1-[(3-chloro-2-fluorophenyl)amino]-6-methylisoquinolin-5-yl}thieno[3,2-d]pyrimidine-7-carboxamide · in 1 record

Elsewhere

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.