GL1X · GenesisL1 explorer

Ligand · VQP

VQP · N-(3,3-dimethylbutyl)-N'-{2-fluoro-5-[(5-fluoro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]-4-methylphenyl}urea

VQP, N-(3,3-dimethylbutyl)-N'-{2-fluoro-5-[(5-fluoro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]-4-methylphenyl}urea (C23 H27 F2 N5 O2, 443.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
VQP
Formula
C23 H27 F2 N5 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

VQP in 2 structures; the first of them:

  • 7K0V · Crystal structure of bRaf in complex with inhibitor GNE-0749 · VQP A801 · binds ILE463, VAL471, ALA481, VAL482, LYS483, GLU501, VAL504, LEU505 and 18 more
  • 7K0V · Crystal structure of braf in complex with inhibitor gne-0749 · VQP A801 · binds ILE463, VAL471, ALA481, VAL482, LYS483, GLU501, VAL504, LEU505 and 18 more

Residues it binds most

ILE 8, LEU 8, VAL 8, PHE 8, THR 8, TRP 8, ALA 8, ASP 8, CYS 8, GLN 8 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.