MolNFT v1 · #169552 · protein
Crystal structure of braf kinase domain bound to belvarafenib
6XFP: “Crystal structure of braf kinase domain bound to belvarafenib”. X-ray diffraction, 2 ligands (V1Y, CL). MolNFT v1 #169552 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6XFP
- Type
- protein
- Length
- 272 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- H7C560
- Ligands
- V1Y, CL
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 272 | — | H7C560 |
Ligands and binding sites
- V1Y · 4-amino-N-{1-[(3-chloro-2-fluorophenyl)amino]-6-methylisoquinolin-5-yl}thieno[3,2-d]pyrimidine-7-carboxamide · ligand · chains A
- CL · Chloride ion · ion · 6 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6XFP · Crystal Structure of BRAF kinase domain bound to Belvarafenib · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt H7C560
- Elsewhere: RCSB PDB 6XFP · PDBe 6XFP · UniProt H7C560
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