UniProt F1SGC6
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (F1SGC6)
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (UniProt F1SGC6): 92 experimental structures on GenesisL1, 5 ligands bound, 452 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- F1SGC6
- Protein
- NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial
- Experimental structures
- 92
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 452 · 92 records with a druggable one
Structures
92 records of F1SGC6 in the MolNFT archive: 92 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5GPN | Architecture of mammalian respirasome | electron microscopy | u, Ai | — | 2 (best 0.81) |
| 5GUP | Cryo-EM structure of mammalian respiratory supercomplex I1III2IV1 | electron microscopy | a | CDL | 3 (best 0.90) |
| 7V2C | Active state complex I from Q10 dataset | electron microscopy | a | CDL, PLX | 4 (best 0.85) |
| 7V2C | Active state complex I from Q10 dataset | electron microscopy | a | CDL, PLX | 4 (best 0.85) |
| 7V2D | Deactive state complex I from Q10 dataset | electron microscopy | a | CDL, PLX | 3 (best 0.91) |
| 7V2D | Deactive state complex I from Q10 dataset | electron microscopy | a | CDL, PLX | 3 (best 0.91) |
| 7V2E | Active state complex I from Q10-NADH dataset | electron microscopy | a | CDL, PLX | 5 (best 0.91) |
| 7V2E | Active state complex I from Q10-NADH dataset | electron microscopy | a | CDL, PLX | 5 (best 0.91) |
| 7V2F | Deactive state complex I from Q10-NADH dataset | electron microscopy | a | CDL, PLX | 4 (best 0.90) |
| 7V2F | Deactive state complex I from Q10-NADH dataset | electron microscopy | a | CDL, PLX | 4 (best 0.90) |
| 7V2H | Active state complex I from DQ-NADH dataset | electron microscopy | a | CDL, PLX | 6 (best 0.89) |
| 7V2H | Active state complex I from dq-NADH dataset | electron microscopy | a | CDL, PLX | 6 (best 0.89) |
| 7V2K | Deactive state complex I from DQ-NADH dataset | electron microscopy | a | CDL, PLX | 6 (best 0.87) |
| 7V2K | Deactive state complex I from dq-NADH dataset | electron microscopy | a | CDL, PLX | 6 (best 0.87) |
| 7V2R | Active state complex I from Q1-NADH dataset | electron microscopy | a | CDL, PLX | 5 (best 0.88) |
| 7V2R | Active state complex I from Q1-NADH dataset | electron microscopy | a | CDL, PLX | 5 (best 0.88) |
| 7V30 | Deactive state complex I from Q1-NADH dataset | electron microscopy | a | CDL, PLX | 5 (best 0.91) |
| 7V30 | Deactive state complex I from Q1-NADH dataset | electron microscopy | a | CDL, PLX | 5 (best 0.91) |
| 7V31 | Active state complex I from rote dataset | electron microscopy | a | CDL, PLX | 7 (best 0.88) |
| 7V31 | Active state complex I from rotenone dataset | electron microscopy | a | CDL, PLX | 7 (best 0.88) |
| 7V32 | Deactive state complex I from rote dataset | electron microscopy | a | CDL, PLX | 6 (best 0.87) |
| 7V32 | Deactive state complex I from rotenone dataset | electron microscopy | a | CDL, PLX | 6 (best 0.87) |
| 7V33 | Active state complex I from rote -NADH dataset | electron microscopy | a | CDL, PLX | 4 (best 0.86) |
| 7V33 | Active state complex I from rotenone-NADH dataset | electron microscopy | a | CDL, PLX | 4 (best 0.86) |
| 7V3M | Deactive state complex I from rote -NADH dataset | electron microscopy | a | CDL, PLX | 4 (best 0.90) |
| 7V3M | Deactive state complex I from rotenone-NADH dataset | electron microscopy | a | CDL, PLX | 4 (best 0.90) |
| 7VBL | Membrane arm of active state CI from DQ-NADH dataset | electron microscopy | a | CDL, PLX | 7 (best 0.89) |
| 7VBL | Membrane arm of active state ci from dq-NADH dataset | electron microscopy | a | CDL, PLX | 7 (best 0.89) |
| 7VBP | Membrane arm of deactive state CI from DQ-NADH dataset | electron microscopy | a | CDL, PLX | 9 (best 0.90) |
| 7VBP | Membrane arm of deactive state ci from dq-NADH dataset | electron microscopy | a | CDL, PLX | 9 (best 0.90) |
| 7VC0 | Membrane arm of active state CI from Rote -NADH dataset | electron microscopy | a | CDL, PLX | 6 (best 0.91) |
| 7VC0 | Membrane arm of active state ci from rotenone-NADH dataset | electron microscopy | a | CDL, PLX | 6 (best 0.91) |
| 7VWL | Membrane arm of deactive state CI from rote -NADH dataset | electron microscopy | a | CDL, PLX | 5 (best 0.90) |
| 7VWL | Membrane arm of deactive state ci from rotenone-NADH dataset | electron microscopy | a | CDL, PLX | 5 (best 0.90) |
| 7VXS | Membrane arm of active state CI from Q10 dataset | electron microscopy | a | CDL, PLX | 8 (best 0.84) |
| 7VY1 | Membrane arm of deactive state CI from Q10 dataset | electron microscopy | a | CDL, PLX | 5 (best 0.89) |
| 7VY9 | Membrane arm of active state CI from Q10-NADH dataset | electron microscopy | a | CDL, PLX | 7 (best 0.91) |
| 7VYE | Membrane arm of deactive state CI from Q10-NADH dataset | electron microscopy | a | CDL, PLX | 7 (best 0.89) |
| 7VYG | Membrane arm of active state CI from rote dataset | electron microscopy | a | CDL, PLX | 6 (best 0.84) |
| 7VYI | Membrane arm of deactive state CI from Rote dataset | electron microscopy | a | CDL, PLX | 7 (best 0.86) |
| 7VYS | Membrane arm of active state CI from Q1-NADH dataset | electron microscopy | a | CDL, PLX | 7 (best 0.88) |
| 7VZ8 | Membrane arm of deactive state CI from Q1-NADH dataset | electron microscopy | a | CDL, PLX | 6 (best 0.89) |
| 7VZV | Active state CI from Q10 dataset, Subclass 1 | electron microscopy | a | CDL, PLX | 4 (best 0.91) |
| 7VZW | Active state CI from Q10 dataset, Subclass 2 | electron microscopy | a | CDL, PLX | 6 (best 0.91) |
| 7W00 | Deactive state CI from Q10 dataset, Subclass 1 | electron microscopy | a | CDL, PLX | 6 (best 0.91) |
| 7W0H | Deactive state CI from Q10 dataset, Subclass 2 | electron microscopy | a | CDL, PLX | 4 (best 0.89) |
| 7W0R | Active state CI from Q10-NADH dataset, Subclass 1 | electron microscopy | a | CDL, PLX | 5 (best 0.89) |
| 7W0Y | Active state CI from Q10-NADH dataset, Subclass 2 | electron microscopy | a | CDL, PLX | 5 (best 0.90) |
| 7W1O | Deactive state CI from Q10-NADH dataset, Subclass 1 | electron microscopy | a | CDL, PLX | 5 (best 0.89) |
| 7W1P | Deactive state CI from Q10-NADH dataset, Subclass 2 | electron microscopy | a | CDL, PLX | 4 (best 0.89) |
| 7W1T | Active state CI from Rote dataset, Subclass 1 | electron microscopy | a | CDL, PLX | 3 (best 0.90) |
| 7W1U | Active state CI from Rote dataset, Subclass 2 | electron microscopy | a | CDL, PLX | 5 (best 0.84) |
| 7W1V | Active state CI from Rote -NADH dataset, Subclass 1 | electron microscopy | a | CDL, PLX | 6 (best 0.88) |
| 7W1Z | Active state CI from Rote -NADH dataset, Subclass 2 | electron microscopy | a | CDL, PLX | 5 (best 0.89) |
| 7W20 | Active state CI from Rote -NADH dataset, Subclass 3 | electron microscopy | a | CDL, PLX | 4 (best 0.88) |
| 7W2K | Deactive state CI from Rote -NADH dataset, Subclass 1 | electron microscopy | a | CDL, PLX | 4 (best 0.90) |
| 7W2L | Deactive state CI from Rote -NADH dataset, Subclass 2 | electron microscopy | a | CDL, PLX | 5 (best 0.91) |
| 7W2R | Active state CI from DQ-NADH dataset, Subclass 1 | electron microscopy | a | CDL, PLX | 4 (best 0.83) |
| 7W2U | Active state CI from DQ-NADH dataset, Subclass 2 | electron microscopy | a | CDL, PLX | 4 (best 0.87) |
| 7W2Y | Active state CI from DQ-NADH dataset, Subclass 3 | electron microscopy | a | CDL, PLX | 3 (best 0.88) |
32 records more on the page itself.
Ligands
- CDL · Cardiolipin · in 80 records
- PLX · (9R,11S)-9-({[(1S)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol · in 72 records
- PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine · in 17 records
- AME · N-acetylmethionine · in 5 records
- 3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine · in 1 record
Elsewhere
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