UniProt B5M9L6
Putative epoxidase LasC (B5M9L6)
Putative epoxidase LasC (UniProt B5M9L6): 4 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 32 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- B5M9L6
- Protein
- Putative epoxidase LasC
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 32 · 5 records with a druggable one
Structures
5 records of B5M9L6 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8UP4 | Crystal structure of Lsd18 (a flavin-dependent monooxygenase) | x-ray diffraction | A, B | FAD, CL | 8 (best 0.87) |
| 8WVB | Crystal structure of Lsd18 mutant S195M | x-ray diffraction | A, B | FAD, CL | 6 (best 0.88) |
| 8WVF | Crystal structure of Lsd18 mutant T189M and S195M | x-ray diffraction | A, B | FAD | 8 (best 0.88) |
| 8WVT | Crystal structure of Lsd18 in complex with ligands | x-ray diffraction | A, B | FAD, X9E, CL, A1LWM | 7 (best 0.87) |
| B5M9L6 | AlphaFold monomer V2.0 prediction for putative epoxidase lasc (B5M9L6) | predicted | A | — | 3 (best 0.85) |
Ligands
- FAD · Flavin-adenine dinucleotide · in 4 records
- CL · Chloride ion · in 3 records
- A1LWM · (4R,5S)-4-methyl-5-phenyl-3-((2R,3S,4S,6E,10E)-2,6,10-triethyl-3-hydroxy-4-methyldodeca-6,10-dienoyl)oxazolidin-2-one · in 1 record
- X9E · (4R,5S)-3-((2R,3S,4S,E)-2,6-diethyl-9-((2R,3R)-2-ethyl-3-methyloxiran-2-yl)-3-hydroxy-4-methylnon-6-enoyl)-4-methyl-5-phenyloxazolidin-2-one · in 1 record
Experiment against prediction
- 8UP4 chain A against the predicted model B5M9L6: TM-score 0.99, RMSD 1.08 Å
- 8WVT chain A against the predicted model B5M9L6: TM-score 0.99, RMSD 1.08 Å
- 8WVB chain B against the predicted model B5M9L6: TM-score 0.99, RMSD 0.94 Å
- 8WVF chain A against the predicted model B5M9L6: TM-score 0.99, RMSD 0.93 Å
- 8WVB chain A against the predicted model B5M9L6: TM-score 0.99, RMSD 0.88 Å
Elsewhere
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