UniProt B3FHP0
Succinate--CoA ligase [ADP-forming] subunit beta (B3FHP0)
Succinate--CoA ligase [ADP-forming] subunit beta (UniProt B3FHP0), EC 6.2.1.5: 12 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 15 pockets. Binding sites, druggability and experiment against…
- UniProt
- B3FHP0
- Protein
- Succinate--CoA ligase [ADP-forming] subunit beta
- EC
- 6.2.1.5
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 15 · 4 records with a druggable one
Structures
13 records of B3FHP0 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6NO0 | ADP bound to ATP-grasp fold of Blastocystis hominis succinyl-CoA synthetase | x-ray diffraction | A, B | ADP, MG, CL | — |
| 6NO0 | ADP bound to ATP-grasp fold of blastocystis hominis succinyl-CoA synthetase | x-ray diffraction | A, B | ADP, MG, CL | — |
| 6NO1 | ADP bound to K46BE mutant ATP-grasp fold of blastocystis hominis succinyl-CoA synthetase | x-ray diffraction | A, B | ADP, MG | — |
| 6NO2 | ADP bound to K114bD mutant ATP-grasp fold of Blastocystis hominis succinyl-CoA synthetase | x-ray diffraction | A, B | ADP, MG, CL | 5 (best 0.66) |
| 6NO2 | ADP bound to K114BD mutant ATP-grasp fold of blastocystis hominis succinyl-CoA synthetase | x-ray diffraction | A, B | ADP, MG, CL | — |
| 6NO3 | ADP bound to V113bL mutant ATP-grasp fold of Blastocystis hominis succinyl-CoA synthetase | x-ray diffraction | A, B | ADP, MG, CL | 5 (best 0.64) |
| 6NO3 | ADP bound to V113BL mutant ATP-grasp fold of blastocystis hominis succinyl-CoA synthetase | x-ray diffraction | A, B | ADP, MG, CL | — |
| 6NO4 | ADP bound to L227bF mutant ATP-grasp fold of Blastocystis hominis succinyl-CoA synthetase | x-ray diffraction | A, B | ADP, MG | 3 (best 0.71) |
| 6NO4 | ADP bound to L227BF mutant ATP-grasp fold of blastocystis hominis succinyl-CoA synthetase | x-ray diffraction | A, B | ADP, MG | — |
| 6NO5 | ADP bound to K46BE&K114BD mutant ATP-grasp fold of blastocystis hominis succinyl-CoA synthetase | x-ray diffraction | A, B, C, D | ADP, MG, NH4 | — |
| 6NO6 | K46bE&K114bD mutant ATP-grasp fold of Blastocystis hominis succinyl-CoA synthetase | x-ray diffraction | A, B | — | — |
| 6NO6 | K46BE&K114BD mutant ATP-grasp fold of blastocystis hominis succinyl- CoA synthetase | x-ray diffraction | A, B | — | — |
| B3FHP0 | AlphaFold monomer V2.0 prediction for succinate--CoA ligase [ADP- forming] subunit beta (B3FHP0) | predicted | A | — | 2 (best 0.73) |
Ligands
Experiment against prediction
- 6NO5 chain C against the predicted model B3FHP0: TM-score 0.98, RMSD 0.84 Å
- 6NO2 chain A against the predicted model B3FHP0: TM-score 0.98, RMSD 0.82 Å
- 6NO2 chain A against the predicted model B3FHP0: TM-score 0.98, RMSD 0.82 Å
- 6NO3 chain B against the predicted model B3FHP0: TM-score 0.98, RMSD 0.92 Å
- 6NO6 chain B against the predicted model B3FHP0: TM-score 0.98, RMSD 0.84 Å
- 6NO6 chain B against the predicted model B3FHP0: TM-score 0.98, RMSD 0.84 Å
- 6NO0 chain B against the predicted model B3FHP0: TM-score 0.98, RMSD 0.88 Å
- 6NO0 chain B against the predicted model B3FHP0: TM-score 0.98, RMSD 0.88 Å
- 6NO1 chain B against the predicted model B3FHP0: TM-score 0.98, RMSD 0.84 Å
- 6NO5 chain D against the predicted model B3FHP0: TM-score 0.98, RMSD 0.95 Å
Elsewhere
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