UniProt A5K8L9
Serine hydroxymethyltransferase, putative (A5K8L9)
Serine hydroxymethyltransferase, putative (UniProt A5K8L9): 19 experimental structures on GenesisL1, 6 ligands bound, 36 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A5K8L9
- Protein
- Serine hydroxymethyltransferase, putative
- Experimental structures
- 19
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 36 · 3 records with a druggable one
Structures
19 records of A5K8L9 in the MolNFT archive: 19 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4OYT | Crystal structure of ternary complex of Plasmodium vivax SHMT with D-serine and folinic acid | x-ray diffraction | A, B, C | — | — |
| 4OYT | Crystal structure of ternary complex of plasmodium vivax shmt with D- serine and folinic acid | x-ray diffraction | A, B, C | — | — |
| 4PFF | Crystal structure of Plasmodium vivax SHMT with PLP Schiff base | x-ray diffraction | A, B, C | — | — |
| 4PFF | Crystal structure of plasmodium vivax shmt with plp schiff base | x-ray diffraction | A, B, C | — | — |
| 4PFN | Crystal structure of Plasmodium vivax SHMT with L-serine Schiff base | x-ray diffraction | A, B, C | — | — |
| 4PFN | Crystal structure of plasmodium vivax shmt with L-serine schiff base | x-ray diffraction | A, B, C | — | — |
| 4TMR | Crystal structure of ternary complex of Plasmodium vivax SHMT with glycine and a novel… | x-ray diffraction | A, B, C | — | — |
| 4TMR | Crystal structure of ternary complex of plasmodium vivax shmt with glycine and a novel… | x-ray diffraction | A, B, C | — | — |
| 4TN4 | Crystal structure of ternary complex of Plasmodium vivax SHMT with glycine and a novel… | x-ray diffraction | A, B, C | — | — |
| 4TN4 | Crystal structure of ternary complex of plasmodium vivax shmt with glycine and a novel… | x-ray diffraction | A, B, C | — | — |
| 5GVK | Plasmodium vivax SHMT bound with PLP-glycine and GS256 | x-ray diffraction | A, B, C | PLG, G45, CL | 13 (best 0.76) |
| 5GVK | Plasmodium vivax shmt bound with plp-glycine and GS256 | x-ray diffraction | A, B, C | — | — |
| 5GVL | Plasmodium vivax shmt bound with plp-glycine and GS182 | x-ray diffraction | A, B, C | — | — |
| 5GVM | Plasmodium vivax SHMT bound with PLP-glycine and GS557 | x-ray diffraction | A, B, C | PLG, G57, CL | 10 (best 0.80) |
| 5GVM | Plasmodium vivax shmt bound with plp-glycine and GS557 | x-ray diffraction | A, B, C | — | — |
| 5GVN | Plasmodium vivax SHMT bound with PLP-glycine and GS653 | x-ray diffraction | A, B, C | G6F, CL | — |
| 5GVN | Plasmodium vivax shmt bound with plp-glycine and GS653 | x-ray diffraction | A, B, C | — | — |
| 5GVP | Plasmodium vivax SHMT bound with PLP-glycine and GS654 | x-ray diffraction | A, B, C | PLG, GCF, CL | 13 (best 0.75) |
| 5GVP | Plasmodium vivax shmt bound with plp-glycine and GS654 | x-ray diffraction | A, B, C | — | — |
Ligands
- CL · Chloride ion · in 4 records
- PLG · N-glycine-[3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-yl-methane] · in 3 records
- G45 · 5-[3-[(4~{S})-6-azanyl-5-cyano-3-methyl-4-propan-2-yl-2~{H}-pyrano[2,3-c]pyrazol-4-yl]-5-cyano-phenyl]-~{N},~{N}-dimethyl-thiophene-2-sulfonamide · in 1 record
- G57 · 2-[3-[3-[(4~{S})-6-azanyl-5-cyano-3-methyl-4-propan-2-yl-2~{H}-pyrano[2,3-c]pyrazol-4-yl]-5-(trifluoromethyl)phenyl]phenyl]ethanoic acid · in 1 record
- G6F · 3-[3-[3-[(4~{S})-6-azanyl-5-cyano-3-methyl-4-propan-2-yl-2~{H}-pyrano[2,3-c]pyrazol-4-yl]-5-fluoranyl-phenyl]phenyl]propanoic acid · in 1 record
- GCF · 3-[3-[3-[(4~{S})-6-azanyl-5-cyano-3-methyl-4-propan-2-yl-2~{H}-pyrano[2,3-c]pyrazol-4-yl]-5-(trifluoromethyl)phenyl]phenyl]propanoic acid · in 1 record
Elsewhere
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