UniProt A0A3C0TX30
2-Hydroxyacyl-CoA Lyase/Synthase (A0A3C0TX30)
2-Hydroxyacyl-CoA Lyase/Synthase (UniProt A0A3C0TX30), EC 4.1.1.8: 4 experimental structures on GenesisL1, 11 ligands bound, 76 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A3C0TX30
- Protein
- 2-Hydroxyacyl-CoA Lyase/Synthase
- EC
- 4.1.1.8
- Experimental structures
- 4
- Predicted models
- 0
- Ligands
- 11
- Pockets
- 76 · 4 records with a druggable one
Structures
4 records of A0A3C0TX30 in the MolNFT archive: 4 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8VZA | Crystal Structure of 2-Hydroxacyl-CoA Lyase/Synthase ApbHACS from Alphaproteobacteria bacterium in… | x-ray diffraction | A, B, C, D | 8FL, UQ3, ADP, ACE, MG | 16 (best 0.88) |
| 8VZB | Crystal Structure of 2-Hydroxacyl-CoA Lyase/Synthase ApbHACS from Alphaproteobacteria bacterium in… | x-ray diffraction | A, B, C, D | MG, 8FL, UQ3, ADP, PO4, CL | 20 (best 0.86) |
| 8VZC | Crystal Structure of 2-Hydroxyacyl-CoA Lyase/Synthse ApbHACS from Alphaproteobacteria bacterium in… | x-ray diffraction | A, B, C, D | A1AEK, FYN, MG, ADP, PO4 | 20 (best 0.86) |
| 8VZF | Crystal Structure of 2-Hydroxyacyl-CoA Lyase/Synthase ApbHACS from Alphaproteobacteria bacterium in… | x-ray diffraction | A, B, C, D | FYN, TPP, MG, ADP, SO4, CL | 20 (best 0.88) |
Ligands
- ADP · Adenosine-5'-diphosphate · in 4 records
- MG · Magnesium ion · in 4 records
- 8FL · 2-[(2R)-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2-oxidanyl-2H-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate · in 2 records
- ACE · Acetyl group · in 2 records
- CL · Chloride ion · in 2 records
- FYN · S-{(9R,13S,15R)-17-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-9,13,15-trihydroxy-10,10-dimethyl-13,15-dioxido-4,8-dioxo-12,14,16-trioxa-3,7-diaza-13,15-diphosphaheptadec-1-yl} thioformate · in 2 records
- PO4 · Phosphate ion · in 2 records
- UQ3 · S-{(3S,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5,10,14-tetraoxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (2R)-2-hydroxypropanethioate · in 2 records
- A1AEK · 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-(hydroxymethyl)-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium · in 1 record
- SO4 · Sulfate ion · in 1 record
- TPP · Thiamine diphosphate · in 1 record
Elsewhere
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