A1AEK · 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-(hydroxymethyl)-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium

Binding sites

A1AEK in 2 structures; the first of them:

• 8VZC · Crystal Structure of 2-Hydroxyacyl-CoA Lyase/Synthse ApbHACS from Alphaproteobacteria… · A1AEK A601 · binds TYR371, GLY392, ALA393, ASN394, THR395, GLY418, THR419, MET420 and 19 more
• 8VZE · Crystal Structure of 2-Hydroxyacyl-CoA lyase/synthase TbHACS from Thermoflexaceae… · A1AEK A601 · binds TYR367, GLY388, ALA389, SER390, THR391, GLY414, THR415, MET416 and 10 more

Residues it binds most

GLY 6, ALA 6, THR 6, ASN 6, ILE 6, MET 6, PHE 6, SER 6, VAL 4, ASP 6 (residue and the binding sites it lines).

Found with

• ADP · Adenosine-5'-diphosphate
• MG · Magnesium ion
• EDO · 1,2-ethanediol
• COA · Coenzyme A
• FYN · S-{(9R,13S,15R)-17-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-9,13,15-trihydroxy-10,10-dimethyl-13,15-dioxido-4,8-dioxo-12,14,16-trioxa-3,7-diaza-13,15-diphosphaheptadec-1-yl} thioformate
• PO4 · Phosphate ion
• PEG · Di(hydroxyethyl)ether