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Ligand · UQ3

UQ3 · S-{(3S,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5,10,14-tetraoxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (2R)-2-hydroxypropanethioate

UQ3, S-{(3S,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5,10,14-tetraoxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl}…

Component
UQ3
Formula
C24 H40 N7 O18 P3 S
Class
ligand
Structures
3
PDB entries
3

Binding sites

UQ3 in 3 structures; the first of them:

  • 8E6O · Crystal structure of human GCN5 histone acetyltransferase domain · UQ3 A701 · binds GLN530, LEU531, ILE576, VAL577, PHE578, CYS579, ALA580, VAL581 and 16 more
  • 8VZA · Crystal Structure of 2-Hydroxacyl-CoA Lyase/Synthase ApbHACS from Alphaproteobacteria… · UQ3 A602 · binds PRO242, GLY257, GLY258, ALA259, ARG260, SER261, TRP279, ILE280 and 17 more
  • 8VZB · Crystal Structure of 2-Hydroxacyl-CoA Lyase/Synthase ApbHACS from Alphaproteobacteria… · UQ3 A603 · binds PRO242, GLY257, GLY258, ALA259, ARG260, SER261, HIS262, TRP279 and 20 more

Residues it binds most

GLY 11, ALA 11, GLN 11, PHE 11, VAL 11, ARG 8, TRP 8, LYS 11, THR 11, ILE 11 (residue and the binding sites it lines).

Found with

  • 8FL · 2-[(2R)-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2-oxidanyl-2H-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate
  • ACE · Acetyl group
  • ADP · Adenosine-5'-diphosphate
  • MG · Magnesium ion
  • CL · Chloride ion
  • PO4 · Phosphate ion
  • ACY · Acetic acid
  • EDO · 1,2-ethanediol
  • GOL · Glycerol
  • PEG · Di(hydroxyethyl)ether

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