GL1X · GenesisL1 explorer

UniProt A0A1S4NYF2

ATP-dependent translocase ABCB1,mNeonGreen (A0A1S4NYF2)

ATP-dependent translocase ABCB1,mNeonGreen (UniProt A0A1S4NYF2), EC 2.7.11.17, 7.6.2.1: 3 experimental structures on GenesisL1, 4 ligands bound, 15 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A1S4NYF2
Protein
ATP-dependent translocase ABCB1,mNeonGreen
EC
2.7.11.17, 7.6.2.1, 7.6.2.2
Experimental structures
3
Predicted models
0
Ligands
4
Pockets
15 · 3 records with a druggable one

Structures

3 records of A0A1S4NYF2 in the MolNFT archive: 3 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8OSIGenetically encoded green ratiometric calcium indicator FNCaMP in calcium-bound statex-ray diffractionACA4 (best 0.69)
8Y6HP-glycoprotein in complex with UIC2 Fab and triple elacridar molecules in LMNG detergentelectron microscopyAR0Z5 (best 0.87)
8Y6IP-glycoprotein in complex with UIC2 Fab and triple elacridar molecules in nanodiscelectron microscopyACLR, 3PE, R0Z6 (best 0.88)

Ligands

  • R0Z · elacridar · in 2 records
  • 3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine · in 1 record
  • CA · Calcium ion · in 1 record
  • CLR · Cholesterol · in 1 record

Experiment against prediction

Elsewhere

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