Ligand · R0Z
R0Z · elacridar
R0Z, elacridar (C34 H33 N3 O5, 563.6 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.
- Component
- R0Z
- Formula
- C34 H33 N3 O5
- Class
- ligand
- Structures
- 4
- PDB entries
- 3
Binding sites
R0Z in 4 structures; the first of them:
- 7A6C · Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and elacridar · R0Z A1301 · binds LEU65, MET69, PHE336, ILE340, GLN725, PHE728, PHE732, GLN946 and 7 more
- 8Y6H · P-glycoprotein in complex with UIC2 Fab and triple elacridar molecules in LMNG detergent · R0Z A1601 · binds LEU65, MET68, MET69, PHE72, PHE336, ILE340, GLN725, PHE728 and 10 more
- 8Y6I · P-glycoprotein in complex with UIC2 Fab and triple elacridar molecules in nanodisc · R0Z A1614 · binds LEU65, MET68, MET69, PHE72, PHE336, ILE340, GLN725, PHE728 and 10 more
- 7A6C · Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and elacridar · R0Z A1301 · binds LEU65, MET69, PHE336, GLN725, PHE728, PHE732, TYR953, SER979 and 2 more
Residues it binds most
PHE 10, GLN 9, MET 7, ILE 9, LEU 10, TYR 8, SER 8, ALA 4, TRP 6, VAL 3 (residue and the binding sites it lines).
Found with
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