UniProt A0A140T871
Glutamate dehydrogenase 1, mitochondrial (A0A140T871)
Glutamate dehydrogenase 1, mitochondrial (UniProt A0A140T871), EC 1.4.1.2, 1.4.1.3: 13 experimental structures on GenesisL1, 9 ligands bound, 140 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A140T871
- Protein
- Glutamate dehydrogenase 1, mitochondrial
- EC
- 1.4.1.2, 1.4.1.3
- Experimental structures
- 13
- Predicted models
- 0
- Ligands
- 9
- Pockets
- 140 · 7 records with a druggable one
Structures
13 records of A0A140T871 in the MolNFT archive: 13 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6DHD | Bovine glutamate dehydrogenase complexed with NADH, GTP, glutamate | x-ray diffraction | A, B, C, D, E, F | GLU, NAI, GTP | 20 (best 0.86) |
| 6DHD | Bovine glutamate dehydrogenase complexed with NADH, GTP, glutamate | x-ray diffraction | A, B, C, D, E, F | NAI, GTP | — |
| 6DHK | Bovine glutamate dehydrogenase complexed with ADP | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | ADP | — |
| 6DHL | Bovine glutamate dehydrogenase complexed with epicatechin-3-gallate (ECG) | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | XEG | 20 (best 0.86) |
| 6DHL | Bovine glutamate dehydrogenase complexed with epicatechin-3-gallate (ecg) | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | XEG | — |
| 6DHM | Bovine glutamate dehydrogenase complexed with zinc | x-ray diffraction | A, B, C, D, E, F | GLU, NDP, GTP, ZN | 20 (best 0.88) |
| 6DHM | Bovine glutamate dehydrogenase complexed with zinc | x-ray diffraction | A, B, C, D, E, F | NDP, GTP, ZN | — |
| 6DHN | Bovine glutamate dehydrogenase complexed with Eu3+ | x-ray diffraction | A, B, C, D, E, F | GLU, GTP, NAI | 20 (best 0.88) |
| 6DHN | Bovine glutamate dehydrogenase complexed with EU3+ | x-ray diffraction | A, B, C, D, E, F | GTP, NAI | — |
| 6DHQ | Bovine glutamate dehydrogenase complexed with NADPH, glutamate, and GTP | x-ray diffraction | A, B, C, D, E, F | GLU, NDP, GTP | 20 (best 0.87) |
| 6DHQ | Bovine glutamate dehydrogenase complexed with NADPH, glutamate, and GTP | x-ray diffraction | A, B, C, D, E, F | NDP, GTP | — |
| 8AR7 | Bovine glutamate dehydrogenase in ternary complex with the allosteric activators ADP and leucine | x-ray diffraction | A, B, C, D, E, F | ADP, K, LEU | 20 (best 0.89) |
| 8AR8 | Bovine glutamate dehydrogenase in complex with ADP at 2.4 A resolution | x-ray diffraction | A, B, C, D, E, F | ADP | 20 (best 0.89) |
Ligands
- GTP · Guanosine-5'-triphosphate · in 8 records
- GLU · Glutamic acid · in 4 records
- NAI · 1,4-dihydronicotinamide adenine dinucleotide · in 4 records
- NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate · in 4 records
- ADP · Adenosine-5'-diphosphate · in 3 records
- XEG · (2R,3S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate · in 2 records
- ZN · Zinc ion · in 2 records
- K · Potassium ion · in 1 record
- LEU · Leucine · in 1 record
Elsewhere
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