Ligand · YP4
YP4 · N-[(1R)-1-(naphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine
YP4, N-[(1R)-1-(naphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine (C22 H22 F3 N, 357.4 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (5 PDB entries). Every binding site with its residues within 4.5 Å…
- Component
- YP4
- Formula
- C22 H22 F3 N
- Class
- ligand
- Structures
- 5
- PDB entries
- 5
Binding sites
YP4 in 5 structures; the first of them:
- 8SZF · Cryo-EM structure of cinacalcet-bound active-state human calcium-sensing receptor CaSR in… · YP4 A1208 · binds PHE668, GLN681, PHE684, GLY685, LEU776, ILE777, THR780, PHE814 and 5 more
- 8SZG · Cryo-EM structure of cinacalcet-bound human calcium-sensing receptor CaSR-Gq complex in… · YP4 A1201 · binds GLN681, PHE684, GLY685, ILE777, THR780, PHE814, TRP818, ILE819 and 4 more
- 8SZH · Cryo-EM structure of cinacalcet-bound human calcium-sensing receptor CaSR-Gi complex in… · YP4 A901 · binds PHE668, GLN681, PHE684, GLY685, LEU776, ILE777, THR780, PHE814 and 6 more
- 8WPU · Human calcium-sensing receptor(CaSR) bound to cinacalcet in complex with Gq protein · YP4 B1105 · binds PHE668, GLN681, PHE684, GLY685, GLU767, LEU770, GLY774, LEU776 and 8 more
- 7M3F · Asymmetric activation of the calcium sensing receptor homodimer · YP4 A905 · binds GLN681, PHE684, ILE777, THR780, TRP818, ILE822, TYR825, GLU837
Residues it binds most
ILE 10, PHE 10, LEU 8, GLU 9, GLN 10, GLY 8, THR 10, TRP 10, TYR 9, CYS 2 (residue and the binding sites it lines).
Found with
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