UW8 · 2-[3,8,8,12,12-pentakis(2-hydroxy-2-oxoethyl)-2,7,11-tris(oxidanylidene)-1,4,6,9,10,13-hexaoxa-5$l^{6}-titanaspiro[4.4^{5}.4^{5}]tridecan-3-yl]ethanoic acid

Binding sites

UW8 in 6 structures; the first of them:

• 7NYP · monomeric acetyl-CoA synthase in closed conformation · UW8 B805 · binds LYS338, LYS349, ARG384
• 7NYS · monomeric acetyl-CoA synthase in closed conformation with carbon monoxide bound to the Ni… · UW8 B804 · binds LYS49, TYR50, LYS123, LYS49, TYR50, LYS123
• 7NZ5 · monomeric acetyl-CoA synthase with Zn at the proximal position of cluster A · UW8 A810 · binds LYS49, TYR50, LYS123, ARG45, LYS49, LYS123
• 7NYP · Monomeric acetyl-CoA synthase in closed conformation · UW8 B805 · binds LYS338, ARG384
• 7NYS · Monomeric acetyl-CoA synthase in closed conformation with carbon monoxide bound to the ni… · UW8 B804 · binds LYS49, TYR50, LYS123, LYS49, LYS123
• 7NZ5 · Monomeric acetyl-CoA synthase with zn at the proximal position of cluster a · UW8 A810 · binds LYS49, TYR50, LYS123, ARG45, LYS49, LYS123

Residues it binds most

LYS 8, TYR 5, ARG 4 (residue and the binding sites it lines).

Found with

• SF4 · Iron/sulfur cluster
• NI · Nickel (II) ion
• PEG · Di(hydroxyethyl)ether
• UWE · $l^{3}-oxidanylidynemethylnickel
• ZN · Zinc ion
• CL · Chloride ion
• BU3 · (R,R)-2,3-butanediol
• CIT · Citric acid
• MLI · Malonate ion