TZD · 2-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-2-oxo-2,3-dihydro-1,3-thiazol-5-yl}ethyl trihydrogen diphosphate

Binding sites

TZD in 14 structures; the first of them:

• 5K6R · Crystal structure of Arabidopsis thaliana acetohydroxyacid synthase in complex with a… · TZD A706 · binds VAL485, GLY486, GLN487, HIS488, GLY511, MET513, GLY537, ASP538 and 9 more
• 5K6T · Crystal structure of Arabidopsis thaliana acetohydroxyacid synthase in complex with a… · TZD A706 · binds VAL485, GLY486, GLN487, HIS488, GLY511, MET513, GLY537, ASP538 and 8 more
• 6DEP · Crystal structure of Candida albicans acetohydroxyacid synthase in complex with the… · TZD A705 · binds VAL493, GLY494, GLN495, HIS496, GLY519, MET521, GLY545, ASP546 and 9 more
• 7EGV · Acetolactate Synthase from Trichoderma harzianum with inhibitor harzianic acid · TZD A702 · binds VAL498, GLY499, GLN500, HIS501, GLY524, MET526, GLY550, ASP551 and 17 more
• 5K6R · Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a… · TZD A706 · binds VAL485, GLY486, GLN487, HIS488, GLY511, MET513, GLY537, ASP538 and 9 more
• 5K6T · Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a… · TZD A706 · binds VAL485, GLY486, GLN487, HIS488, GLY511, MET513, GLY537, ASP538 and 8 more
• 6DEP · Crystal structure of candida albicans acetohydroxyacid synthase in complex with the… · TZD A705 · binds VAL493, GLY494, GLN495, HIS496, GLY519, MET521, GLY545, ASP546 and 9 more
• 6DER · Crystal structure of candida albicans acetohydroxyacid synthase in complex with the… · TZD A705 · binds VAL493, GLY494, GLN495, HIS496, GLY519, MET521, GLY545, ASP546 and 9 more
• 6DES · Crystal structure of candida albicans acetohydroxyacid synthase in complex with the… · TZD A705 · binds VAL493, GLY494, GLN495, HIS496, GLY519, MET521, GLY545, ASP546 and 9 more
• 6XN8 · Crystal structure of 2-hydroxyacyl CoA lyase (hacl) from rhodospirillales bacterium… · TZD A602 · binds TYR367, GLY388, ALA389, GLY390, THR391, GLY414, MET416, GLY440 and 15 more
• 7EGV · Acetolactate synthase from trichoderma harzianum with inhibitor harzianic acid · TZD A702 · binds VAL498, GLY499, GLN500, HIS501, GLY524, MET526, GLY550, ASP551 and 17 more
• 7EHE · Acetolactate synthase from trichoderma harzianum · TZD A703 · binds VAL498, GLY499, GLN500, HIS501, GLY524, MET526, GLY550, ASP551 and 16 more
• 7STQ · Crystal structure of arabidopsis thaliana acetohydroxyacid synthase W574L mutant in… · TZD A704 · binds VAL485, GLY486, GLN487, HIS488, GLY511, MET513, GLY537, ASP538 and 9 more
• 7U25 · Crystal structure of arabidopsis thaliana acetohydroxyacid synthase W574L mutant in… · TZD A704 · binds VAL485, GLY486, GLN487, HIS488, GLY511, MET513, GLY537, ASP538 and 9 more

Residues it binds most

GLY 18, MET 18, VAL 18, GLN 18, ASN 18, HIS 18, ASP 18, GLU 12, SER 18, ALA 12 (residue and the binding sites it lines).

Found with

• MG · Magnesium ion
• FAD · Flavin-adenine dinucleotide
• K · Potassium ion
• NHE · 2-[N-cyclohexylamino]ethane sulfonic acid
• SO4 · Sulfate ion
• 6R4 · methyl 2-[(4-methyl-5-oxidanylidene-3-propoxy-1,2,4-triazol-1-yl)carbonylsulfamoyl]benzoate
• TP9 · (3Z)-4-{[(4-amino-2-methylpyrimidin-5-yl)methyl]amino}-3-mercaptopent-3-en-1-yl trihydrogen diphosphate
• 1SM · Methyl 2-[({[(4,6-dimethylpyrimidin-2-yl) amino]carbonyl}amino)sulfonyl]benzoate
• 6R5 · methyl 4-[(3-methoxy-4-methyl-5-oxidanylidene-1,2,4-triazol-1-yl)carbonylsulfamoyl]-5-methyl-thiophene-3-carboxylate
• J3L · (2S)-3-methyl-2-[[(2S,4R)-1-methyl-4-[(2E,4E)-octa-2,4-dienoyl]-3,5-bis(oxidanylidene)pyrrolidin-2-yl]methyl]-2-oxidanyl-butanoic acid
• PO4 · Phosphate ion
• EDO · 1,2-ethanediol