PSC · (7R,17E,20E)-4-hydroxy-N,N,N-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosa-17,20-dien-1-aminium 4-oxide

Binding sites

PSC in 63 structures; the first of them:

• 5B3S · Bovine heart cytochrome c oxidase in the carbon monoxide-bound mixed-valence state at… · PSC B303 · binds PHE268, PHE321, LEU324, ALA325, HIS328, LEU37, ILE41, MET45 and 20 more
• 5IY5 · Electron transfer complex of cytochrome c and cytochrome c oxidase at 2.0 angstrom… · PSC E201 · binds PHE268, PHE321, LEU324, ALA325, HIS328, LEU37, ILE41, MET45 and 19 more
• 5W97 · Crystal Structure of CO-bound Cytochrome c Oxidase determined by Serial Femtosecond X-Ray… · PSC B302 · binds PHE268, PHE321, LEU324, ALA325, HIS328, LEU37, ILE41, MET45 and 19 more
• 5WAU · Crystal Structure of CO-bound Cytochrome c Oxidase determined by Synchrotron X-Ray… · PSC E201 · binds PHE268, PHE321, LEU324, ALA325, HIS328, ILE41, MET45, HIS52 and 16 more
• 5X1B · CO bound cytochrome c oxidase at 20 nsec after pump laser irradiation to release CO from… · PSC B303 · binds ALA325, HIS328, HIS52, MET56, ASP57, GLU60, VAL61, TRP65 and 10 more
• 5X1F · CO bound cytochrome c oxidase without pump laser irradiation at 278K · PSC B303 · binds PHE321, ALA325, HIS328, HIS52, ASP57, VAL61, TRP65, LEU68 and 7 more
• 5XDQ · Bovine heart cytochrome c oxidase in the fully oxidized state with pH 7.3 at 1.77… · PSC B303 · binds PHE268, PHE321, LEU324, ALA325, HIS328, LEU37, ILE41, MET45 and 19 more
• 5XDX · Bovine heart cytochrome c oxidase in the reduced state with pH 7.3 at 1.99 angstrom… · PSC E201 · binds PHE268, PHE321, LEU324, ALA325, HIS328, LEU37, ILE41, MET45 and 21 more
• 5Z85 · The structure of azide-bound cytochrome c oxidase determined using the another batch… · PSC B302 · binds PHE321, LEU324, ALA325, HIS328, LEU37, ILE41, MET45, HIS52 and 13 more
• 5ZCO · azide-bound cytochrome c oxidase structure determined using the crystals exposed to 2 mM… · PSC E201 · binds PHE268, PHE321, LEU324, ALA325, HIS328, LEU37, ILE41, MET45 and 15 more
• 5ZCP · azide-bound cytochrome c oxidase structure determined using the crystals exposed to 20 mM… · PSC B303 · binds PHE268, PHE321, LEU324, ALA325, HIS328, LEU37, ILE41, MET45 and 15 more
• 5ZCQ · Azide-bound cytochrome c oxidase structure determined using the crystals exposed to 10 mM… · PSC B303 · binds PHE321, LEU324, ALA325, HIS328, ILE41, MET45, HIS52, MET56 and 11 more
• 6J8M · Low-dose structure of bovine heart cytochrome c oxidase in the fully oxidized state… · PSC E201 · binds PHE268, PHE321, LEU324, ALA325, HIS328, LEU37, ILE41, MET45 and 15 more
• 6JUW · Bovine heart cytochrome C oxidase in catalitic intermediates at 1.80 ångström resolution · PSC A609 · binds PHE321, LEU324, ALA325, HIS328, LEU37, VAL38, ILE41, HIS52 and 10 more
• 6NMF · SFX structure of reduced cytochrome c oxidase at room temperature · PSC B304 · binds PHE268, PHE321, LEU324, ALA325, HIS328, LEU37, ILE41, MET45 and 16 more
• 6NMP · SFX structure of oxidized cytochrome c oxidase at room temperature · PSC B302 · binds PHE268, PHE321, LEU324, ALA325, HIS328, LEU37, ILE41, MET45 and 17 more
• 7CP5 · Bovine heart cytochrome c oxidase in a catalytic intermediate of E at 1.76 angstrom… · PSC A607 · binds PHE268, PHE321, LEU324, ALA325, HIS328, LEU37, ILE41, MET45 and 12 more
• 7D5W · Bovine heart cytochrome c oxidase in a catalytic intermediate of O at 1.84 angstrom… · PSC A610 · binds PHE268, PHE321, LEU324, ALA325, HIS328, ILE34, LEU37, ILE41 and 11 more
• 7D5X · Bovine heart cytochrome c oxidase in a catalytic intermediate, IO10, at 1.74 angstrom… · PSC B303 · binds PHE268, PHE321, LEU324, ALA325, HIS328, MET45, HIS52, MET56 and 7 more
• 7EV7 · Bovine heart cytochrome c oxidase in the carbon monoxide-bound fully reduced state at a… · PSC B302 · binds PHE268, PHE321, LEU324, ALA325, HIS328, LEU37, ILE41, HIS52 and 14 more

Residues it binds most

LEU 130, ILE 115, PHE 129, HIS 122, ASP 121, MET 124, ALA 120, GLU 103, VAL 123, TRP 118 (residue and the binding sites it lines).

Found with

• CDL · Cardiolipin
• ZN · Zinc ion
• CUA · Dinuclear copper ion
• HEA · Heme-A
• PEK · (1S)-2-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(stearoyloxy)methyl]ethyl (5E,8E,11E,14E)-icosa-5,8, 11,14-tetraenoate
• PGV · (1R)-2-{[{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl (11E)-octadec-11-enoate
• CU · Copper (II) ion
• MG · Magnesium ion
• NA · Sodium ion
• CHD · Cholic acid
• TGL · Tristearoylglycerol
• DMU · Decyl-beta-D-maltopyranoside