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Ligand · OTS

OTS · 4-(2S-amino-1-hydroxyethyl)phenol

OTS, 4-(2S-amino-1-hydroxyethyl)phenol (C8 H11 N O2, 153.2 g/mol), in the MolNFT structures on GenesisL1: bound in 11 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
OTS
Formula
C8 H11 N O2
Class
ligand
Structures
11
PDB entries
6

Binding sites

OTS in 11 structures; the first of them:

  • 1RG1 · Crystal structure of human Tyrosyl-DNA Phosphodiesterase complexed with vanadate… · OTS A997 · binds DT806, TYR204, CYS205, HIS263, ASN283, GLY458, SER459, PRO461 and 1 more
  • 1RG2 · Crystal structure of human Tyrosyl-DNA Phosphodiesterase complexed with vanadate… · OTS A995 · binds DA806, TYR204, CYS205, HIS263, ASN283, GLY458, SER459, PRO461 and 2 more
  • 1RGT · Crystal structure of human Tyrosyl-DNA Phosphodiesterase complexed with vanadate… · OTS A995 · binds DC806, TYR204, CYS205, HIS263, ASN283, GLY458, SER459, PRO461 and 1 more
  • 1RGU · The crystal structure of human Tyrosyl-DNA Phosphodiesterase complexed with vanadate… · OTS A995 · binds DG806, TYR204, CYS205, HIS263, ASN283, GLY458, SER459, PRO461 and 1 more
  • 1RH0 · Crystal structure of human Tyrosyl-DNA Phosphodiesterase complexed with vanadate… · OTS A995 · binds DT806, TYR204, CYS205, HIS263, ASN283, GLY458, SER459, PRO461 and 1 more
  • 8EEF · C. ammoniagenes monoamine oxidase (MAO) bound to octopamine · OTS A501 · binds TRP58, PHE175, ALA178, GLY179, TRP195, THR210, LEU211, PHE341 and 2 more
  • 1RG1 · Crystal structure of human tyrosyl-DNA phosphodiesterase complexed with vanadate… · OTS A997 · binds DT806, TYR204, CYS205, HIS263, ASN283, GLY458, SER459, PRO461 and 1 more
  • 1RG2 · Crystal structure of human tyrosyl-DNA phosphodiesterase complexed with vanadate… · OTS A995 · binds DA806, TYR204, CYS205, HIS263, ASN283, GLY458, SER459, PRO461 and 2 more
  • 1RGT · Crystal structure of human tyrosyl-DNA phosphodiesterase complexed with vanadate… · OTS A995 · binds DC806, TYR204, CYS205, HIS263, ASN283, GLY458, SER459, PRO461 and 1 more
  • 1RGU · The crystal structure of human tyrosyl-DNA phosphodiesterase complexed with vanadate… · OTS A995 · binds DG806, TYR204, CYS205, HIS263, ASN283, GLY458, SER459, PRO461 and 1 more
  • 1RH0 · Crystal structure of human tyrosyl-DNA phosphodiesterase complexed with vanadate… · OTS A995 · binds DT806, TYR204, CYS205, HIS263, ASN283, GLY458, SER459, PRO461 and 1 more

Residues it binds most

HIS 20, GLY 21, ASN 20, CYS 20, PRO 20, SER 20, TYR 20, TRP 13, DT 8, DA 4 (residue and the binding sites it lines).

Found with

  • SPM · Spermine
  • VO4 · Vanadate ion
  • OTR · 4-(2R-amino-1-hydroxyethyl)phenol
  • FAD · Flavin-adenine dinucleotide

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