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Ligand · OSM

OSM · 1-(oxidosulfanyl)methanamine

OSM, 1-(oxidosulfanyl)methanamine (C H5 N O S, 79.1 g/mol), in the MolNFT structures on GenesisL1: bound in 19 records (14 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found…

Component
OSM
Formula
C H5 N O S
Class
ligand
Structures
19
PDB entries
14

Binding sites

OSM in 19 structures; the first of them:

  • 5B72 · Crystal structure of bovine lactoperoxidase with a broken covalent bond between Glu258… · OSM A802 · binds THR23, ILE24, THR25, PRO197
  • 5GLS · Structure of bovine Lactoperoxidase with a partially modified covalent bond with heme… · OSM A727 · binds GLU363, TYR365, ARG397, HIS558, ILE559, THR560, LYS561
  • 5WV3 · Crystal structure of bovine lactoperoxidase with a partial Glu258-heme linkage at 2.07 A… · OSM A609 · binds TYR85, LEU86, ASP87, LYS411
  • 6KY7 · Crystal structure of yak lactoperoxidase at 2.27 A resolution · OSM A620 · binds HIS377, THR378, HIS429
  • 6LCO · Crystal structure of bovine lactoperoxidase with substrates thiocynate and iodide bound… · OSM A631 · binds ASN230, SER235, PRO236, CYS248, PHE254
  • 6LF7 · Crystal structure of the complex of goat lactoperoxidase with hypothiocyanite and… · OSM A622 · binds GLN105, HIS109, ARG255, GLU258, PHE381
  • 7DLQ · Crystal structure of the complex of lactoperoxidase with hydrogen peroxide at 1.77A… · OSM A617 · binds ASN230, LYS232, SER235, PRO236, CYS248, PHE254, PHE381
  • 5WV3 · Crystal structure of bovine lactoperoxidase with a partial GLU258-heme linkage at 2.07 a… · OSM A609 · binds TYR85, LEU86, ASP87

Residues it binds most

ARG 36, ASN 37, PRO 34, LYS 26, HIS 19, GLU 21, PHE 18, THR 17, LEU 14, SER 13 (residue and the binding sites it lines).

Found with

  • HEM · Protoporphyrin IX containing Fe
  • CA · Calcium ion
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • IOD · Iodide ion
  • SCN · Thiocyanate ion
  • PEO · Hydrogen peroxide
  • EDO · 1,2-ethanediol
  • GOL · Glycerol
  • ZN · Zinc ion
  • NA · Sodium ion
  • BR · Bromide ion
  • BMA · beta-D-mannopyranose

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