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Ligand · LBV

LBV · 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid

LBV, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrro…

Component
LBV
Formula
C33 H37 N4 O6 +1
Class
ligand
Structures
36
PDB entries
26

Binding sites

LBV in 36 structures; the first of them:

  • 5K5B · Wild-type PAS-GAF fragment from Deinococcus radiodurans BphP · LBV A405 · binds THR20, THR21, CYS24, GLU27, ILE29, MET174, TYR176, PHE198 and 19 more
  • 5LBR · Wild-type PAS-GAF fragment from Deinococcus radiodurans Bphp collected at SACLA · LBV A401 · binds THR20, THR21, CYS24, GLU27, ILE29, MET174, TYR176, VAL186 and 23 more
  • 5LLW · Bacteriophytochrome activated diguanylyl cyclase from Idiomarina species A28L · LBV B701 · binds CYS17, GLU20, ILE22, MSE166, TYR168, VAL178, PHE195, SER198 and 25 more
  • 5MG0 · Structure of PAS-GAF fragment of Deinococcus phytochrome by serial femtosecond… · LBV A401 · binds CYS24, GLU27, ILE29, MET174, TYR176, PHE198, PHE203, SER206 and 15 more
  • 5NFX · Deinococcus radiodurans BphP PAS-GAF Y263F mutant · LBV A405 · binds THR20, THR21, CYS24, GLU27, ILE29, MET174, TYR176, VAL186 and 23 more
  • 5NWN · Deinococcus radiodurans BphP PAS-GAF-PHY Y263F mutant, dark · LBV A600 · binds THR21, CYS24, GLU27, ILE29, MET174, TYR176, PHE198, PHE203 and 18 more
  • 6FHT · Crystal structure of an artificial phytochrome regulated adenylate/guanylate cyclase in… · LBV A801 · binds THR20, THR21, CYS24, GLU27, ILE29, MET174, TYR176, VAL186 and 24 more
  • 6SAX · Chromophore binding domain of bacteriophytochrome linked diguanylyl cyclase from… · LBV B401 · binds CYS17, GLU20, ILE22, MET166, TYR168, VAL178, PHE195, SER198 and 25 more
  • 7Z9D · Deinococcus radiodurans BphP PAS-GAF H260A mutant · LBV A405 · binds THR20, THR21, CYS24, GLU27, ILE29, MET174, TYR176, PHE198 and 19 more
  • 7Z9E · Deinococcus radiodurans BphP PAS-GAF H260A/Y263F mutant · LBV A405 · binds THR20, THR21, CYS24, GLU27, ILE29, MET174, TYR176, VAL186 and 24 more
  • 8BOR · Photosensory module from DrBphP without PHY tongue · LBV A800 · binds THR20, THR21, CYS24, GLU27, ILE29, MET174, TYR176, VAL186 and 24 more
  • 8C3I · Dark state of PAS-GAF fragment from Deinococcus radiodurans phytochrome · LBV B401 · binds THR20, THR21, CYS24, GLU27, ILE29, MET174, TYR176, PHE198 and 22 more
  • 8SGK · CryoEM structure of Deinococcus radiodurans BphP photosensory module in Pr state · LBV A801 · binds THR21, CYS24, ILE29, TYR176, PHE198, PHE203, SER206, ASP207 and 20 more
  • 8U8Z · Cryo-EM structure of PsBphP in Pr state, extended DHp · LBV A900 · binds CYS16, GLU19, ILE21, LEU170, TYR172, PHE194, PHE199, SER202 and 24 more
  • 9EUT · Cryo-EM structure of the full-length Pseudomonas aeruginosa bacteriophytochrome in its Pr… · LBV A2000 · binds CYS12, GLU15, ILE17, MET161, TYR163, TYR185, TYR190, SER193 and 25 more
  • 9EUY · Cryo-EM structure of the full-length Pseudomonas aeruginosa bacteriophytochrome in its… · LBV A1000 · binds LEU9, CYS12, GLU13, ILE17, TYR163, TYR185, GLN188, TYR190 and 24 more
  • 5K5B · Wild-type pas-gaf fragment from deinococcus radiodurans bphp · LBV A405 · binds THR20, THR21, CYS24, GLU27, ILE29, MET174, TYR176, PHE198 and 19 more
  • 5L8M · Wild-type pas-gaf fragment from deinococcus radiodurans bphp collected at lcls · LBV A401 · binds THR21, CYS24, GLU27, ILE29, MET174, TYR176, PHE198, PHE203 and 18 more
  • 5LBR · Wild-type pas-gaf fragment from deinococcus radiodurans bphp collected at sacla · LBV A401 · binds CYS24, GLU27, ILE29, MET174, TYR176, PHE198, PHE203, SER206 and 16 more
  • 5LLW · Bacteriophytochrome activated diguanylyl cyclase from idiomarina species A28L · LBV B701 · binds CYS17, ILE22, MSE166, TYR168, VAL178, PHE195, SER198, ASP199 and 21 more
  • 5LLX · Bacteriophytochrome activated diguanylyl cyclase from idiomarina species A28L with GTP… · LBV A701 · binds CYS17, ILE22, MET166, TYR168, VAL178, PHE195, SER198, ASP199 and 19 more
  • 5LLY · Photosensory module of bacteriophytochrome linked diguanylyl cyclase from idiomarina… · LBV D601 · binds CYS17, GLU20, ILE22, MET166, TYR168, VAL178, PHE195, SER198 and 21 more

Residues it binds most

SER 73, TYR 74, ILE 74, HIS 74, LEU 72, PHE 70, MET 69, ARG 74, ALA 66, THR 53 (residue and the binding sites it lines).

Found with

  • ACT · Acetate ion
  • MPD · (4S)-2-methyl-2,4-pentanediol
  • CL · Chloride ion
  • NI · Nickel (II) ion
  • SO4 · Sulfate ion
  • 12P · Dodecaethylene glycol
  • EDO · 1,2-ethanediol
  • GTP · Guanosine-5'-triphosphate
  • MG · Magnesium ion
  • GOL · Glycerol

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