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Ligand · IZL

IZL · [(2~{R})-3-[[(1~{S},2~{R},3~{S},4~{S},5~{R},6~{R})-2-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-[[(2~{S},3~{S}, 4~{S},5~{S},6~{R})-6-[[(2~{S},3~{S},4~{S},5~{S}, 6~{R})-6-(hydroxymethyl)-3-[(2~{R},3~{S},4~{S},5~{S}, 6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4,5-bis(oxidanyl)oxan-2-yl]oxymethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxymethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-3,4,5-tris(oxidanyl)-6-[(2~{R},3~{S},4~{S},5~{S},6~{R})-3,4,5-tris(oxidanyl)-6-(undecanoyloxymethyl)oxan-2-yl]oxy-cyclohe

IZL, [(2~{R})-3-[[(1~{S},2~{R},3~{S},4~{S},5~{R},6~{R})-2-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-[[(2~{S},3~{S}, 4~{S},5~{S},6~{R})-6-[[(2~{S},3~{S},4~{S},5~{S}, 6~{R})-6-(hydroxymethyl)-3-[(2~{R},3~{S},4~{S},5~{S}…

Component
IZL
Formula
C74 H133 O39 P
Class
ligand
Structures
4
PDB entries
3

Binding sites

IZL in 4 structures; the first of them:

  • 7QHO · Cytochrome bcc-aa3 supercomplex (respiratory supercomplex III2/IV2) from Corynebacterium… · IZL A502 · binds ILE186, TRP190, TRP206, THR211, GLU214, ASN394, PHE395, ILE396 and 13 more
  • 9FU0 · CIII2/CIV respiratory chain supercomplex from Mycobacterium smegmatis · IZL M504 · binds TRP224, LYS235, ALA236, TRP239, TRP417, GLU418, ARG419, LYS420 and 6 more
  • 7QHM · Cytochrome bcc-AA3 supercomplex (respiratory supercomplex III2/IV2) from corynebacterium… · IZL A502 · binds ILE186, TRP190, TRP206, GLU214, ASN394, PHE395, GLU397, PRO398 and 11 more
  • 7QHO · Cytochrome bcc-AA3 supercomplex (respiratory supercomplex III2/IV2) from corynebacterium… · IZL A502 · binds TRP190, TRP206, GLU214, ASN394, PHE395, ILE396, GLU397, PRO398 and 9 more

Residues it binds most

TRP 8, ILE 8, GLU 8, ASN 6, LYS 8, ARG 8, PHE 6, PRO 6, TYR 6, MET 5 (residue and the binding sites it lines).

Found with

  • 3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine
  • 9YF · (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1r,2r,3r,4r, 5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate
  • CDL · Cardiolipin
  • FES · Fe2/s2 (inorganic) cluster
  • HEC · Heme C
  • HEM · Protoporphyrin IX containing Fe
  • MQ9 · Menaquinone-9
  • PLM · Palmitic acid
  • CA · Calcium ion
  • CU · Copper (II) ion
  • CUA · Dinuclear copper ion
  • DGA · Diacyl glycerol

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