Ligand · GZX

GZX · (1~{S},3~{S},7~{S},10~{R},11~{S},12~{S},16~{R})-8,8,10, 12,16-pentamethyl-3-[(~{E})-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-7,11-bis(oxidanyl)-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione

GZX, (1~{S},3~{S},7~{S},10~{R},11~{S},12~{S},16~{R})-8,8,10, 12,16-pentamethyl-3-[(~{E})-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-7,11-bis(oxidanyl)-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione (C27 H42 N2 O5 S, 506.7 g/mol), in…

Component: GZX
Formula: C27 H42 N2 O5 S
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

GZX in 2 structures; the first of them:

7DAF · IXA in complex with tubulin · GZX D503 · binds LEU215, LEU217, ASP224, HIS227, LEU228, ALA231, PHE270, PRO272 and 8 more
7DAF · Ixa in complex with tubulin · GZX D503 · binds LEU215, LEU217, ASP224, HIS227, LEU228, ALA231, PHE270, PRO272 and 8 more

Residues it binds most

LEU 2, ARG 2, ALA 2, ASP 2, GLN 2, HIS 2, PHE 2, PRO 2, SER 2, THR 2 (residue and the binding sites it lines).

Found with

ACP · Phosphomethylphosphonic acid adenylate ester
GDP · Guanosine-5'-diphosphate
GTP · Guanosine-5'-triphosphate
CA · Calcium ion
MG · Magnesium ion
CL · Chloride ion
MES · 2-(N-morpholino)-ethanesulfonic acid

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