Ligand · GTF
GTF · 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate)
GTF, 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate) (C9 H14 F2 N3 O13 P3, 503.1 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the…
- Component
- GTF
- Formula
- C9 H14 F2 N3 O13 P3
- Class
- ligand
- Structures
- 5
- PDB entries
- 4
Binding sites
GTF in 5 structures; the first of them:
- 6DW5 · SAMHD1 Bound to Gemcitabine-TP in the Catalytic Pocket · GTF A701 · binds GLN149, LEU150, ARG164, ARG206, ASN207, HIS210, HIS215, HIS233 and 8 more
- 8FV6 · E coli. CTP synthase in complex with dF-dCTP · GTF AAA602 · binds VAL186, LYS187, THR188, LYS189, GLN192, LYS223, PHE227, SER14 and 4 more
- 8FV7 · E coli. CTP synthase in complex with dF-dCTP + ATP · GTF BBB701 · binds SER14, THR144, ASP147, ILE148, GLU149, VAL186, LYS187, THR188 and 4 more
- 8FV8 · E coli. CTP synthase in complex with dF-dCTP + ADP · GTF AAA602 · binds SER14, THR144, ASP147, ILE148, GLU149, VAL186, LYS187, THR188 and 4 more
- 6DW5 · SAMHD1 bound to gemcitabine-tp in the catalytic pocket · GTF A701 · binds GLN149, LEU150, ARG164, ARG206, ASN207, HIS210, HIS215, HIS233 and 8 more
Residues it binds most
HIS 8, LYS 14, ARG 8, ASP 14, GLN 14, TYR 8, THR 6, ASN 8, LEU 8, GLU 6 (residue and the binding sites it lines).
Found with
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