GL1X · GenesisL1 explorer

Ligand · GBL

GBL · Gamma-butyrolactone

GBL, Gamma-butyrolactone (C4 H6 O2, 86.1 g/mol), in the MolNFT structures on GenesisL1: bound in 19 records (10 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
GBL
Formula
C4 H6 O2
Class
ligand
Structures
19
PDB entries
10

Binding sites

GBL in 19 structures; the first of them:

  • 2VWD · Nipah Virus Attachment Glycoprotein · GBL A1603 · binds SER447, LEU448, PHE512, LEU513, ILE514, CYS565, PHE566, LEU567 and 1 more
  • 2WD1 · Human c-Met Kinase in complex with azaindole inhibitor · GBL A2348 · binds MET1131, LEU1140, SER1141, LEU1142, LEU1157, PHE1223, GLY1224, LEU1225 and 1 more
  • 3F66 · Human c-Met Kinase in complex with quinoxaline inhibitor · GBL A3 · binds ARG1208, ASN1209, MET1211, ALA1221, ASP1222, ALA1226, TYR1230
  • 3SFZ · Crystal structure of full-length murine Apaf-1 · GBL A1251 · binds SER387, ILE388, LEU389, GLN390, THR446, LEU453, HIS457, TYR489
  • 3SHF · Crystal structure of the R265S mutant of full-length murine Apaf-1 · GBL A1251 · binds SER387, ILE388, LEU389, GLN390, THR446, LEU453, HIS457, TYR489 and 1 more
  • 4EHQ · Crystal Structure of Calmodulin Binding Domain of Orai1 in Complex with Ca2+/Calmodulin… · GBL A205 · binds ASN97, GLY98, TYR99, ASN137
  • 4KNB · C-Met in complex with OSI ligand · GBL A1402 · binds SER1331, GLU1332, SER1335
  • 4R1V · Identification and optimization of pyridazi s as potent and selective c-Met kinase… · GBL A1402 · binds MET1131, LEU1140, SER1141, LEU1142, LEU1157, PHE1223, GLY1224, LEU1225 and 1 more
  • 7D9X · Highly active mutant W525D of Gamma-glutamyltranspeptidase from Pseudomonas nitroreducens · GBL A401 · binds ASP186, TYR187, GLN199, PRO200, GLU201
  • 2CBI · Structure of the clostridium perfringens nagj family 84 glycoside hydrolase, a homologue… · GBL A1627 · binds ASP297, VAL331, TYR335, THR366, VAL370, TRP394, ASN396
  • 2VWD · Nipah virus attachment glycoprotein · GBL A1603 · binds SER447, LEU448, PHE512, LEU513, ILE514, CYS565, PHE566, LEU567 and 1 more

Residues it binds most

LEU 28, PHE 32, ASP 36, TYR 34, SER 26, ASN 22, MET 25, ALA 18, GLY 20, GLU 22 (residue and the binding sites it lines).

Found with

  • ADP · Adenosine-5'-diphosphate
  • CL · Chloride ion
  • GOL · Glycerol
  • 1RU · 7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine
  • 3E8 · 3-[1-(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}benzyl)-6-oxo-1,6-dihydropyridazin-3-yl]benzonitrile
  • IHX · 3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol
  • ZZY · 1-[(2-nitrophenyl)sulfonyl]-1H-pyrrolo[3,2-b]pyridine-6-carboxamide
  • CA · Calcium ion
  • NA · Sodium ion
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • GLY · Glycine
  • ZN · Zinc ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.