Ligand · 1RU

1RU · 7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine

1RU, 7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine (C23 H22 Cl2 F N5 O2, 490.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component: 1RU
Formula: C23 H22 Cl2 F N5 O2
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

1RU in 2 structures; the first of them:

4KNB · C-Met in complex with OSI ligand · 1RU A1401 · binds ILE1084, GLY1085, VAL1092, ALA1108, LEU1140, LEU1157, PRO1158, TYR1159 and 11 more
4KNB · C-met in complex with osi ligand · 1RU A1401 · binds ILE1084, GLY1085, VAL1092, ALA1108, LEU1140, LEU1157, PRO1158, TYR1159 and 11 more

Residues it binds most

ALA 8, GLY 8, LEU 8, MET 8, TYR 8, ARG 8, ASN 8, ASP 8, HIS 8, ILE 8 (residue and the binding sites it lines).

Found with

GBL · Gamma-butyrolactone

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