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Ligand · FS2

FS2 · Fe-S-O hybrid cluster

FS2, Fe-S-O hybrid cluster (Fe4 O3 S2, 335.5 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (7 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
FS2
Formula
Fe4 O3 S2
Class
ligand
Structures
8
PDB entries
7

Binding sites

FS2 in 8 structures; the first of them:

  • 7DE4 · Hybrid cluster protein (HCP) from Escherichia coli · FS2 A602 · binds HIS249, GLU273, TRP297, ASN316, CYS317, CSS405, ASP406, CYS433 and 3 more
  • 7WSX · Class III hybrid cluster protein (HCP) C67Y variant from Methanothermobacter marburgensis · FS2 A601 · binds HIS193, SER216, GLU217, TRP241, ASN260, CYS261, CSS347, ASP348 and 3 more
  • 8OIP · 28S mammalian mitochondrial small ribosomal subunit with mtRF1 and P-site tRNA · FS2 AP201 · binds CYS105, GLY107, ILE108, LYS65, CYS66, CYS69, GLU70, CYS101 and 1 more
  • 8OIR · 55S human mitochondrial ribosome with mtRF1 and P-site tRNA · FS2 Bh201 · binds SER63, CYS64, GLN69, CYS70, ILE72, CYS73, LYS78, CYS108 and 1 more
  • 8OIS · 28S human mitochondrial small ribosomal subunit with mtRF1 and P-site tRNA · FS2 AP201 · binds CYS105, GLY107, ILE108, LYS63, LYS64, CYS65, CYS68, GLY69 and 3 more
  • 8OIT · 39S human mitochondrial large ribosomal subunit with mtRF1 and P-site tRNA · FS2 Bh201 · binds SER63, CYS64, GLN69, CYS70, ILE72, CYS73, LYS78, CYS108 and 1 more
  • 7DE4 · Hybrid cluster protein (hcp) from escherichia COLI · FS2 A602 · binds HIS249, GLU273, TRP297, ASN316, CYS317, CSS405, CYS433, CYS458 and 2 more
  • 7E0L · Hybrid cluster protein (hcp) from methanothermobacter marburgensis · FS2 A601 · binds HIS193, GLU217, TRP241, ASN260, CYS261, CSS347, CYS375, CYS400 and 3 more

Residues it binds most

CYS 16, LYS 12, GLU 11, ASN 8, CSS 8, GLY 6, HIS 8, TRP 8, ASP 5, ILE 5 (residue and the binding sites it lines).

Found with

  • K · Potassium ion
  • MG · Magnesium ion
  • ZN · Zinc ion
  • ATP · Adenosine-5'-triphosphate
  • GDP · Guanosine-5'-diphosphate
  • MET · Methionine
  • SF4 · Iron/sulfur cluster
  • VAL · Valine
  • SPD · Spermidine
  • SPM · Spermine
  • FE · Fe (III) ion

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