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Ligand · F8L

F8L · [(2Z,6E,10E,14Z,18E,22Z,26Z)-3,7,11,15,19,23,27,31,35, 39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl] [(2S,3S,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl] hydrogen phosphate

F8L, [(2Z,6E,10E,14Z,18E,22Z,26Z)-3,7,11,15,19,23,27,31,35, 39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl] [(2S,3S,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl] hydrogen phosphate (C55 H91 O8 P, 911.3 g/mol), in the…

Component
F8L
Formula
C55 H91 O8 P
Class
ligand
Structures
6
PDB entries
3

Binding sites

F8L in 6 structures; the first of them:

  • 7BVC · Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in… · F8L A1102 · binds ASP261, TYR264, ASN265, GLU289, PHE292, GLN296, ARG365, PRO366 and 18 more
  • 7BVG · Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in… · F8L A1101 · binds ASP261, TYR264, ASN265, ILE268, GLU289, PHE292, GLN296, ARG365 and 14 more
  • 7BWR · Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound… · F8L A2002 · binds TYR288, ASN304, TRP308, GLU313, PRO315, PHE316, ILE421, ALA425 and 17 more
  • 7BVC · Cryo-EM structure of mycobacterium smegmatis arabinosyltransferase emba-embb-ACPM2 in… · F8L A1102 · binds ASP261, TYR264, ASN265, PHE292, GLN296, ARG365, PRO408, GLN409 and 9 more
  • 7BVG · Cryo-EM structure of mycobacterium smegmatis arabinosyltransferase emba-embb-ACPM2 in… · F8L A1101 · binds ASP261, TYR264, ASN265, GLU289, PHE292, ARG365, PRO366, PRO408 and 8 more
  • 7BWR · Mycobacterium smegmatis arabinosyltransferase complex EMBB2-ACPM2 in substrate dpa bound… · F8L A2002 · binds TYR288, TRP308, GLU313, PHE316, ILE421, ALA425, LEU428, VAL438 and 11 more

Residues it binds most

LEU 6, PRO 5, GLN 4, PHE 6, TYR 6, VAL 5, THR 6, ILE 3, ASN 5, ARG 6 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • CDL · Cardiolipin
  • PNS · 4'-phosphopantetheine
  • PO4 · Phosphate ion
  • 95E · Ethambutol
  • BXY · alpha-D-arabinofuranose

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