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Ligand · CRH

CRH · 1,2-hydro-1-oxy-3,4-hydro-3-(1-methoxy-2-oxy-3,4-dihydroxypentyl)-8,9-dihyroxy-7-methylanthracene

CRH, 1,2-hydro-1-oxy-3,4-hydro-3-(1-methoxy-2-oxy-3,4-dihydroxypentyl)-8,9-dihyroxy-7-methylanthracene (C21 H24 O7, 388.4 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its…

Component
CRH
Formula
C21 H24 O7
Class
ligand
Structures
6
PDB entries
3

Binding sites

CRH in 6 structures; the first of them:

  • 146D · Solution structure of the mithramycin dimer-DNA complex · CRH A9 · binds DG3, DC4, DG5, DA6, DG11
  • 207D · Solution structure of mithramycin dimers bound to partially overlapping sites on DNA · CRH A13 · binds DA2, DG3, DC4, DT5, DT9
  • 6J0I · Structure of [Co2+-(Chromomycin A3)2]-d(TTGGCGAA)2 complex · CRH A103 · binds DG4, DC5, DG6, DA7, DG14
  • 146D · Solution structure of the mithramycin dimer-DNA complex · CRH A9 · binds DG3, DC4, DG5, DA6, DG11
  • 207D · Solution structure of mithramycin dimers bound to partially overlapping sites on DNA · CRH A13 · binds DA2, DG3, DC4, DT5, DT9
  • 6J0I · Structure of [CO2+-(chromomycin A3)2]-D(TTGGCGAA)2 complex · CRH A103 · binds DG4, DC5, DG6, DA7, DG14

Residues it binds most

DG 24, DC 24, DA 24, DT 8 (residue and the binding sites it lines).

Found with

  • DDA · beta-D-Olivopyranose
  • MG · Magnesium ion
  • DDL · 2,6-dideoxy-beta-D-galactopyranose
  • MDA · 2,6-dideoxy-3-C-methyl-beta-D-ribo-hexopyranose
  • 1GL · 2,6-dideoxy-4-O-methyl-alpha-D-galactopyranose
  • ARI · (2R,3R,6R)-6-hydroxy-2-methyltetrahydro-2H-pyran-3-yl acetate
  • CDR · (2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol
  • ERI · 3-C-methyl-4-O-acetyl-alpha-L-Olivopyranose
  • CO · Cobalt (II) ion

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