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Ligand · CPH

CPH · (1S)-5-deoxy-1-O-methyl-1-C-[(2R,3S)-3,5,7,10-tetrahydroxy-6-methyl-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl]-D-xylulose

CPH, (1S)-5-deoxy-1-O-methyl-1-C-[(2R,3S)-3,5,7,10-tetrahydroxy-6-methyl-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl]-D-xylulose (C21 H24 O9, 420.4 g/mol), in the MolNFT structures on GenesisL1: bound in 16 records (8 PDB entries). Every…

Component
CPH
Formula
C21 H24 O9
Class
ligand
Structures
16
PDB entries
8

Binding sites

CPH in 16 structures; the first of them:

  • 1D83 · Structure refinement of the chromomycin DIMER/DNA oligomer complex in solution · CPH A33 · binds DG3, DG4, DC5, DC6, DT7, DC15, DC16
  • 1EKH · NMR structure of D(TTGGCCAA)2 bound to chromomycin-A3 and cobalt · CPH A33 · binds DG3, DG4, DC5, DC6, DA7, DC15, DC16
  • 1EKI · Average solution structure of D(TTGGCCAA)2 bound to chromomycin-A3 and cobalt · CPH A33 · binds DG3, DG4, DC5, DC6, DA7, DC15, DC16
  • 1VAQ · Crystal structure of the Mg2+-(chromomycin A3)2-d(TTGGCCAA)2 complex reveals GGCC binding… · CPH A33 · binds DG3, DG4, DC5, DC6, DA7, DC13, DC14
  • 5XEW · Crystal structure of the [Ni2+-(chromomycin A3)2]-CCG repeats complex · CPH A106 · binds DG5, DG8, DC9, DC10, DG11, DC23
  • 5XJW · Crystal Structure of the [Co2+-(Chromomycin A3)2]-CCG repeats Complex · CPH A106 · binds DG5, DG8, DC9, DC10, DG11, DC23
  • 5YZE · Crystal structure of the [Co2+-(chromomycin A3)2]-d(CCG)3 complex · CPH A106 · binds DG4, DG7, DC8, DC9, DG10, DC20
  • 6L76 · Crystal structure of the Ni(II)(Chro)2-d(TTGGGCCGAA/TTCGGCCCAA) complex at 2.94 angstrom… · CPH A103 · binds DG4, DG5, DC6, DC7, DC16, DC17
  • 1D83 · Structure refinement of the chromomycin DIMER/DNA oligomer complex in solution · CPH A33 · binds DG3, DG4, DC5, DC6, DT7, DC15, DC16
  • 1EKH · NMR structure of D(TTGGCCAA)2 bound to chromomycin-A3 and cobalt · CPH A33 · binds DG3, DG4, DC5, DC6, DA7, DC15, DC16
  • 1EKI · Average solution structure of D(TTGGCCAA)2 bound to chromomycin-A3 and cobalt · CPH A33 · binds DG3, DG4, DC5, DC6, DA7, DC15, DC16
  • 1VAQ · Crystal structure of the MG2+-(chromomycin A3)2-D(TTGGCCAA)2 complex reveals ggcc binding… · CPH A33 · binds DG3, DG4, DC5, DC6, DA7, DC13, DC14
  • 5XEW · Crystal structure of the [NI2+-(chromomycin A3)2]-ccg repeats complex · CPH A106 · binds DG5, DG8, DC9, DC10, DG11, DC23
  • 5XJW · Crystal structure of the [CO2+-(chromomycin A3)2]-ccg repeats complex · CPH A106 · binds DG5, DG8, DC9, DC10, DG11, DC23
  • 5YZE · Crystal structure of the [CO2+-(chromomycin A3)2]-D(CCG)3 complex · CPH A106 · binds DG4, DG7, DC8, DC9, DG10, DC20
  • 6L76 · Crystal structure of the NI(II)(CHRO)2-D(TTGGGCCGAA/TTCGGCCCAA) complex at 2.94 ångström… · CPH A103 · binds DG4, DG5, DC6, DC7, DC16, DC17

Residues it binds most

DC 40, DG 40, DA 18, DT 4 (residue and the binding sites it lines).

Found with

  • 1GL · 2,6-dideoxy-4-O-methyl-alpha-D-galactopyranose
  • ERI · 3-C-methyl-4-O-acetyl-alpha-L-Olivopyranose
  • ARI · (2R,3R,6R)-6-hydroxy-2-methyltetrahydro-2H-pyran-3-yl acetate
  • CDR · (2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol
  • CO · Cobalt (II) ion
  • 2GL · 4-O-acetyl-2,6-dideoxy-beta-D-galactopyranose
  • DDA · beta-D-Olivopyranose
  • MG · Magnesium ion
  • NI · Nickel (II) ion

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