Ligand · CF0
CF0 · Fluoromethane
CF0, Fluoromethane (C H3 F, 34.0 g/mol), in the MolNFT structures on GenesisL1: bound in 29 records (29 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.
- Component
- CF0
- Formula
- C H3 F
- Class
- ligand
- Structures
- 29
- PDB entries
- 29
Binding sites
CF0 in 29 structures; the first of them:
- 1CP3 · Crystal structure of the complex of apopain with the tetrapeptide inhibitor ACE-dvad-fmc · CF0 C994 · binds HIS121, GLY122, CYS163, TYR204, ALA992, ASP993
- 1JXQ · Structure of cleaved, card domain deleted caspase-9 · CF0 E506 · binds HIS237, CYS285, VAL504, ASP505
- 1X3Z · Structure of a PEPTIDE:N-glycanase-RAD23 complex · CF0 I4 · binds ARG190, CYS191, GLY192, HIS218, ALA2, ASP3
- 2F4O · The mouse pngase-HR23 complex reveals a complete remodulation of the protein-protein… · CF0 I5 · binds CYS306, GLY307, ASP332, HIS333, ALA3, ASP4
- 2H48 · Crystal structure of human caspase-1 (CYS362->ala, CYS364->ala, CYS397->ala) in complex… · CF0 C5 · binds HIS237, GLY238, CYS285, ALA3, ASP4
- 2H4W · Crystal structure of human caspase-1 (GLU390->asp) in complex with 3… · CF0 C5 · binds GLY238, CYS285, ALA3, ASP4
- 2H4Y · Crystal structure of human caspase-1 (ARG286->lys) in complex with 3… · CF0 C5 · binds HIS237, GLY238, CYS285, ALA3, ASP4
- 2H51 · Crystal structure of human caspase-1 (GLU390->asp and ARG286->lys) in complex with… · CF0 C5 · binds HIS237, GLY238, CYS285, ALA3, ASP4
- 2H54 · Crystal structure of human caspase-1 (THR388->ala) in complex with 3… · CF0 C5 · binds GLY238, CYS285, ALA3, ASP4
- 2H6M · An episulfide cation (thiiranium ring) trapped in the active site of hav 3C proteinase… · CF0 I6 · binds MET29, HIS44, CYS172, VAL192, ALA4, QMM5
- 2H9H · An episulfide cation (thiiranium ring) trapped in the active site of hav 3C proteinase… · CF0 I6 · binds MET29, HIS44, CYS172, VAL192, ALA4, QMM5
- 2HAL · An episulfide cation (thiiranium ring) trapped in the active site of hav 3C proteinase… · CF0 I6 · binds MET29, HIS44, GLY170, MET171, CYS172, PHE4, GLK5
- 2HBQ · Crystal structure of wildtype human caspase-1 in complex with 3-[2-(2… · CF0 C5 · binds GLY238, CYS285, ALA3, ASP4
- 2HBR · Crystal structure of human caspase-1 (ARG286->ala) in complex with 3… · CF0 C5 · binds HIS237, GLY238, CYS285, ALA3, ASP4
- 2HBY · Crystal structure of human caspase-1 (GLU390->ala) in complex with 3… · CF0 C5 · binds HIS237, GLY238, CYS285, ALA3, ASP4
- 2HBZ · Crystal structure of human caspase-1 (ARG286->ala, GLU390->ala) in complex with… · CF0 C5 · binds HIS237, GLY238, CYS285, ALA3, ASP4
- 3D6F · Crystal structure of human caspase-1 with a naturally-occurring ARG240->gln substitution… · CF0 C5 · binds GLY238, CYS285, ALA3, ASP4
- 3D6H · Crystal structure of human caspase-1 with a naturally-occurring ASN263->ser substitution… · CF0 C5 · binds HIS237, GLY238, CYS285, ALA3, ASP4
- 3D6M · Crystal structure of human caspase-1 with a naturally-occurring LYS319->arg substitution… · CF0 C5 · binds CYS285, ALA3, ASP4
- 3QNW · Caspase-6 in complex with Z-vad-fmk inhibitor · CF0 X5 · binds CYS163, ARG164, SER218, VAL2, ALA3, ASP4
- 3V4L · Mouse MALT1(CASPASE-IG3 domains) in complex with a irreversible peptidic inhibitor · CF0 B6 · binds HIS423, CYS472, PRO4, ARG5
- 3V4O · Human MALT1 (caspase domain) in complex with an irreversible peptidic inhibitor · CF0 B6 · binds HIS415, CYS464, PRO4, ARG5
- 4DM9 · The crystal structure of ubiquitin carboxy-terminal hydrolase L1 (UCHL1) bound to a… · CF0 X5 · binds CYS90, PHE160, ALA3, GME4
- 5D61 · Moa-Z-vad-fmk complex, direct orientation · CF0 L5 · binds CYS215, ALA256, HIS257, ALA258, ALA3, ASP4
- 5D62 · Moa-Z-vad-fmk complex, inverted orientation · CF0 L5 · binds CYS215, ALA256, HIS257, ALA258, ALA3, ASP4
- 5D63 · Moa-Z-vad-fmk inhibitor complex, DIRECT/INVERTED dual orientation · CF0 L5 · binds CYS215, ALA256, HIS257, ALA258, ALA3, ASP4
- 7AEG · SARS-cov-2 main protease in a covalent complex with sdz 224015 derivative, compound 5 · CF0 B5 · binds HIS41, CYS145, ALA3, ASP4
- 7C8B · Crystal structure of the SARS-cov-2 main protease in complex with Z- VAD(OME)-fmk · CF0 D5 · binds HIS41, CYS145, ALA3, FL64
- 7CUT · Crystal structure of the SARS-cov-2 (COVID-19) main protease in complex with Z-vad-fmk · CF0 B5 · binds CYS145, HIS163, HIS164, ALA3, FL64
Residues it binds most
ALA 29, CYS 34, ASP 25, HIS 23, GLY 16, VAL 7, ARG 4, MET 3, PHE 3, FL6 2 (residue and the binding sites it lines).
Found with
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