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Ligand · AF

AF · 2-aminofluorene

AF, 2-aminofluorene (C13 H11 N, 181.2 g/mol), in the MolNFT structures on GenesisL1: bound in 18 records (9 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
AF
Formula
C13 H11 N
Class
ligand
Structures
18
PDB entries
9

Binding sites

AF in 18 structures; the first of them:

  • 1AX6 · Solution structure of the [af]-C8-dg adduct opposite a-2 deletion site in the nari hot… · AF A23 · binds DG5, DC6, DG7, DC8, DG17, DC18, DC19
  • 1AX7 · Solution structure of the [af]-C8-dg adduct positioned at a template-primer junction… · AF A23 · binds DA2, DC3, DG4, DC5, DG22
  • 1C0Y · Solution structure of the [af]-C8-dg adduct positioned opposite da at a template-primer… · AF A24 · binds DA2, DC3, DG4, DC5, DG22, DC23
  • 1UA0 · Aminofluorene DNA adduct at the pre-insertion site of a DNA polymerase · AF C333 · binds DT2, DG3, GLN704, ALA707, VAL708, GLY711, ILE716, LEU721 and 3 more
  • 1UA1 · Structure of aminofluorene adduct paired opposite cytosine at the polymerase active site. · AF C327 · binds DT26, DG27, GLY715, ILE716, SER717, GLY720, GLN723, ASN724
  • 3KHG · Dpo4 extension ternary complex with misinserted A opposite the 2-aminofluorene-guanine… · AF E926 · binds SER103, GLU106, DG813, DG906, DC907
  • 3KHH · Dpo4 extension ternary complex with a C base opposite the 2-aminofluorene-guanine [AF]G… · AF E926 · binds GLY246, ARG247, ILE248, HIS285, VAL287, SER297, VAL335, ARG336 and 3 more
  • 3KHL · Dpo4 post-extension ternary complex with misinserted A opposite the… · AF E926 · binds GLY246, ARG247, ILE248, HIS285, VAL286, VAL287, SER297, GLY334 and 5 more
  • 3KHR · Dpo4 post-extension ternary complex with the correct C opposite the… · AF E926 · binds GLY246, ARG247, ILE248, HIS285, VAL287, GLY334, VAL335, ARG336 and 3 more
  • 1AX6 · Solution structure of the [af]-C8-dg adduct opposite a-2 deletion site in the nari hot… · AF A23 · binds DG5, DC6, DG7, DC8, DG17, DC18, DC19
  • 1AX7 · Solution structure of the [af]-C8-dg adduct positioned at a template- primer junction… · AF A23 · binds DA2, DC3, DG4, DC5, DG22
  • 1C0Y · Solution structure of the [af]-C8-dg adduct positioned opposite da at a template-primer… · AF A24 · binds DA2, DC3, DG4, DC5, DG22, DC23
  • 1UA0 · Aminofluorene DNA adduct at the pre-insertion site of a DNA polymerase · AF C333 · binds DT2, DG3, GLN704, ALA707, VAL708, GLY711, ILE716, LEU721 and 3 more
  • 1UA1 · Structure of aminofluorene adduct paired opposite cytosine at the polymerase active site. · AF C327 · binds DT26, DG27, GLY715, ILE716, SER717, GLY720, GLN723, ASN724
  • 3KHG · DPO4 extension ternary complex with misinserted a opposite the 2- aminofluorene-guanine… · AF E926 · binds SER103, GLU106, DG813, DG906, DC907
  • 3KHH · DPO4 extension ternary complex with a C base opposite the 2- aminofluorene-guanine [AF]G… · AF E926 · binds GLY246, ARG247, ILE248, HIS285, VAL287, SER297, VAL335, ARG336 and 3 more
  • 3KHL · DPO4 post-extension ternary complex with misinserted a opposite the 2… · AF E926 · binds GLY246, ARG247, ILE248, HIS285, VAL286, VAL287, SER297, GLY334 and 5 more
  • 3KHR · DPO4 post-extension ternary complex with the correct C opposite the 2… · AF E926 · binds GLY246, ARG247, ILE248, HIS285, VAL287, GLY334, VAL335, ARG336 and 3 more

Residues it binds most

DC 22, DG 26, VAL 12, ARG 12, GLY 14, ILE 14, SER 12, HIS 10, DA 6, ALA 2 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • DGT · 2'-deoxyguanosine-5'-triphosphate
  • TTP · Thymidine-5'-triphosphate
  • SO4 · Sulfate ion
  • FRU · beta-D-fructofuranose
  • GLC · alpha-D-glucopyranose
  • EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid
  • 2DA · 2',3'-dideoxyadenosine-5'-monophosphate

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