Ligand · 5IS

5IS · (1S,2R,3S,5S,6S,16E,18E,20R)-11-chloro-6-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18,21-hexaene-8,23-dione

5IS, (1S,2R,3S,5S,6S,16E,18E,20R)-11-chloro-6-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18,21-hexaene-8,23-dione (C28 H35 Cl N2 O7, 547.0 g/mol), in the…

Component: 5IS
Formula: C28 H35 Cl N2 O7
Class: ligand
Structures: 1
PDB entries: 1

Binding sites

5IS in 1 structure; the first of them:

5SB8 · Tubulin-maytansinoid-3-complex · 5IS D503 · binds GLY100, ASN102, LYS105, THR180, VAL181, VAL182, PHE404, TRP407

Residues it binds most

VAL 1, ASN 1, GLY 1, LYS 1, PHE 1, THR 1, TRP 1 (residue and the binding sites it lines).

Found with

ACP · Phosphomethylphosphonic acid adenylate ester
GDP · Guanosine-5'-diphosphate
GTP · Guanosine-5'-triphosphate
CA · Calcium ion
MG · Magnesium ion
IMD · Imidazole
MES · 2-(N-morpholino)-ethanesulfonic acid

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