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Ligand · 5I0

5I0 · [(2~{S},3~{S},4~{S},5~{R},6~{S})-2-[(2~{R},3~{R},4~{R},5~{S})-2-[(1~{R},2~{S},3~{R},4~{R},5~{S},6~{R})-2,4-bis[[azaniumylidene(azanyl)methyl]amino]-3,5,6-tris(oxidanyl)cyclohexyl]oxy-4-[bis(oxidanyl)methyl]-5-methyl-4-oxidanyl-oxolan-3-yl]oxy-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-3-yl]-methyl-azanium

5I0, [(2~{S},3~{S},4~{S},5~{R},6~{S})-2-[(2~{R},3~{R},4~{R},5~{S})-2-[(1~{R},2~{S},3~{R},4~{R},5~{S},6~{R})-2,4-bis[[azaniumylidene(azanyl)methyl]amino]-3,5,6-tris(oxidanyl)cyclohexyl]oxy-4-[bis(oxidanyl)methyl]-5-methyl-4-oxidanyl-oxolan-3…

Component
5I0
Formula
C21 H44 N7 O13 +3
Class
ligand
Structures
4
PDB entries
4

Binding sites

5I0 in 4 structures; the first of them:

  • 7P2E · Human mitochondrial ribosome small subunit in complex with IF3, GMPPMP and streptomycin · 5I0 A1703 · binds U654, U655, U656, C898, G899, C1165, A1166, A1167 and 6 more
  • 8CAI · Streptomycin and Hygromycin B bound to the 30S body · 5I0 A1606 · binds U12, U13, U14, C526, G7M527, C912, A913, A914 and 8 more
  • 8CGJ · Streptomycin bound to the 30S body · 5I0 A1603 · binds U12, U13, U14, C526, G7M527, C912, A913, A914 and 8 more
  • 8VXB · Structure of ANT(6)-Ib from Campylobacter fetus subsp fetus complexed with hydrated… · 5I0 A401 · binds GLU29, ASP46, GLN74, PRO76, GLU77, MET79, PHE82, GLU85 and 5 more

Residues it binds most

U 3, A 3, LYS 3, C 3, GLU 1, PRO 4, G 3, ASP 1, D2T 2, G7M 2 (residue and the binding sites it lines).

Found with

  • K · Potassium ion
  • MG · Magnesium ion
  • ATP · Adenosine-5'-triphosphate
  • FES · Fe2/s2 (inorganic) cluster
  • GNP · Phosphoaminophosphonic acid-guanylate ester
  • HY0 · Hygromycin B variant
  • NAD · Nicotinamide-adenine-dinucleotide
  • SCM · Spectinomycin
  • SPM · Spermine
  • TAC · Tetracycline
  • ZN · Zinc ion
  • PO4 · Phosphate ion

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