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Ligand · TAC

TAC · Tetracycline

TAC, Tetracycline (C22 H24 N2 O8, 444.4 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
TAC
Formula
C22 H24 N2 O8
Class
ligand
Structures
5
PDB entries
4

Binding sites

TAC in 5 structures; the first of them:

  • 5J7L · Structure of the 70S E coli ribosome with the U1052G mutation in the 16S rRNA bound to… · TAC AA1680 · binds 2MG966, C1054, C1195, A1196, A1197, G1198, C1400
  • 6FPL · TETR(D) E147A mutant in complex with tetracycline and magnesium · TAC A301 · binds LEU60, HIS64, SER67, ASN82, PHE86, HIS100, ARG104, PRO105 and 5 more
  • 8CF1 · Tetracycline bound to the 30S head · TAC A1601 · binds G1053, C1054, C1195, A1196, A1197, G1198
  • 6FPL · TETR(D) E147A mutant in complex with tetracycline and magnesium · TAC A301 · binds LEU60, HIS64, SER67, ASN82, PHE86, HIS100, ARG104, PRO105 and 5 more
  • 6FPM · TETR(D) T103A mutant in complex with tetracycline and magnesium · TAC A301 · binds HIS64, SER67, ASN82, PHE86, HIS100, PRO105, THR112, VAL113 and 4 more

Residues it binds most

A 5, C 5, G 5, HIS 3, SER 3, ARG 4, ASN 3, GLN 3, ILE 3, LEU 3 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • CL · Chloride ion
  • GUN · Guanine
  • PUT · 1,4-diaminobutane
  • SPD · Spermidine
  • K · Potassium ion
  • ZN · Zinc ion
  • 1PE · Pentaethylene glycol
  • ACY · Acetic acid
  • EDO · 1,2-ethanediol
  • MPD · (4S)-2-methyl-2,4-pentanediol
  • PEG · Di(hydroxyethyl)ether

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