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Ligand · GLV

GLV · Glyoxylic acid

GLV, Glyoxylic acid (C2 H2 O3, 74.0 g/mol), in the MolNFT structures on GenesisL1: bound in 19 records (13 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
GLV
Formula
C2 H2 O3
Class
ligand
Structures
19
PDB entries
13

Binding sites

GLV in 19 structures; the first of them:

  • 5CC5 · Crystal structure of Mycobacterium tuberculosis malate synthase in complex with… · GLV A803 · binds ARG339, MET432, GLU434, GLY459, PHE460, LEU461, ASP462, TRP541 and 1 more
  • 5E9G · Structural insights of isocitrate lyases from Magnaporthe oryzae · GLV A601 · binds TYR104, SER106, GLY107, TRP108, ASP177, HIS204, ARG252, TRP403 and 2 more
  • 5ECX · Klebsiella pneumoniae DfrA1 complexed with NADPH and… · GLV B204 · binds ASP141, PHE142, ALA143, ASN37, GLN38, TRP39, LYS57, THR90
  • 5H8U · Crystal structure of mycobacterium tuberculosis wild-type malate synthase in complex with… · GLV B803 · binds ASP274, ARG339, GLU434, GLY459, PHE460, LEU461, ASP462, TRP541 and 1 more
  • 5XR3 · SAV0551 with glyoxylate · GLV A401 · binds ASP177, ASP181, PRO207
  • 6C4C · Crystal structure of 3-nitropropionate modified isocitrate lyase from Mycobacterium… · GLV A501 · binds TYR89, SER91, GLY92, TRP93, ASP108, ASP153, HIS180, EJA191 and 4 more
  • 6OVL · 2.1 Angstrom structure of wild type Glyoxylate/Hydroxypyruvate reductase A from… · GLV A404 · binds TRP45, GLY64, ALA65, GLY66, MET95, ARG227, HIS275, THR280
  • 6OXN · 2.6 Angstrom structure of W45F/H46S Glyoxylate/Hydroxypyruvate reductase A from… · GLV A403 · binds GLY64, ALA65, GLY66, MET95, ARG227, HIS275
  • 6WSI · Intact cis-2,3-epoxysuccinic acid bound to Isocitrate Lyase-1 from Mycobacterium… · GLV A503 · binds TYR89, SER91, GLY92, TRP93, ASP108, ASP153, HIS180, ARG228 and 3 more
  • 7CMY · Isocitrate lyase from Bacillus cereus ATCC 14579 in complex with Magnessium ion… · GLV C503 · binds TYR85, SER87, GLY88, TRP89, ASP104, ASP148, HIS175, GLU177 and 4 more
  • 5TAO · Haloferax volcanii malate synthase LEAD(II) complex · GLV A502 · binds ASP52, ARG84, GLU158, GLY189, VAL191, ASP192, TRP257
  • 5XR3 · SAV0551 with glyoxylate · GLV A401 · binds ASP181
  • 6C4C · Crystal structure of 3-nitropropionate modified isocitrate lyase from mycobacterium… · GLV A501 · binds TYR89, SER91, GLY92, TRP93, ASP108, ASP153, HIS180, EJA191 and 3 more
  • 6G1O · Structure of pseudomonas aeruginosa isocitrate lyase, icl · GLV A502 · binds ASP117, SER119, ASP186, GLU213, GLN215, SER217, ARG260
  • 6OVL · 2.1 ångström structure of wild type GLYOXYLATE/HYDROXYPYRUVATE reductase a from… · GLV A404 · binds GLY64, ALA65, GLY66, MET95, ARG227, HIS275
  • 6OXN · 2.6 ångström structure of W45F/H46S GLYOXYLATE/HYDROXYPYRUVATE reductase a from… · GLV A403 · binds GLY64, ALA65, GLY66, ARG227, HIS275
  • 6WSI · Intact cis-2,3-epoxysuccinic acid bound to isocitrate lyase-1 from mycobacterium… · GLV A503 · binds TYR89, SER91, GLY92, TRP93, ASP108, ASP153, HIS180, ARG228 and 2 more
  • 7CMY · Isocitrate lyase from bacillus cereus atcc 14579 in complex with magnessium ion… · GLV C503 · binds TYR85, SER87, GLY88, TRP89, ASP104, ASP148, HIS175, ARG223 and 1 more
  • 7RB1 · Isocitrate lyase-1 from mycobacterium tuberculosis covalently modified by… · GLV D501 · binds TYR89, SER91, GLY92, TRP93, ASP153, HIS180, ARG228, THR347 and 1 more

Residues it binds most

ASP 34, TRP 28, GLY 30, ARG 32, HIS 28, SER 24, THR 25, TYR 23, LEU 15, GLU 8 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • GOL · Glycerol
  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate
  • NA · Sodium ion
  • K · Potassium ion
  • 3NP · 3-nitropropanoic acid
  • PYR · Pyruvic acid
  • U9S · (2R,3S)-oxirane-2,3-dicarboxylic acid
  • PO4 · Phosphate ion
  • PEG · Di(hydroxyethyl)ether
  • SIN · Succinic acid
  • 48J · Dihydroxyacetic acid

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