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Ligand · 3WV

3WV · N,2-dimethyl-L-alanyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl}-3-methoxy-5-methyl-1-oxoheptan-4-yl]-N-methyl-L-valinamide

3WV, N,2-dimethyl-L-alanyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl}-3-methoxy-5-methyl-1-oxoheptan-4-yl]-N-methyl-L-valinamide (C38 H63 N5 O8, 717.9 g/mol), in…

Component
3WV
Formula
C38 H63 N5 O8
Class
ligand
Structures
2
PDB entries
1

Binding sites

3WV in 2 structures; the first of them:

  • 4X1Y · Discovery of cytotoxic Dolastatin 10 analogs with N-terminal modifications · 3WV B503 · binds GLN15, PRO175, LYS176, VAL177, SER178, ASP179, THR221, PRO222 and 12 more
  • 4X1Y · Discovery of cytotoxic dolastatin 10 analogs with N-terminal modifications · 3WV B503 · binds GLN15, PRO175, LYS176, VAL177, SER178, ASP179, THR221, PRO222 and 12 more

Residues it binds most

PRO 4, VAL 4, ASN 2, GLN 4, THR 4, TYR 4, ARG 4, ASP 4, GLY 4, LYS 4 (residue and the binding sites it lines).

Found with

  • GDP · Guanosine-5'-diphosphate
  • GTP · Guanosine-5'-triphosphate
  • LOC · N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide
  • MG · Magnesium ion

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