MolNFT v2 · #63927 · protein + DNA

Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases

3FOE: “Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases”. X-ray diffraction at 4.001. MolNFT v2 #63927 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3FOE
Type: protein + DNA
Length: 1,327 residues
Chains: 8
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 4.001
Source: Streptococcus pneumoniae; SYNTHETIC CONSTRUCT
UniProt: P72525, Q59961

Structure

x-ray diffraction · resolution 4.001 · 8 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	432	—	P72525
B	—	protein	433	—	P72525
C	—	protein	196	—	Q59961
D	—	protein	198	—	Q59961
E	—	dna	15	—	—
F	—	dna	19	—	—
G	—	dna	15	—	—
H	—	dna	19	—	—

Compared structures

3FOE · Structural insight into the quinolone-DNA cleavage complex of type iia topoisomerases · the same entry in another collection · chain H against H, TM-score 1.00
P72525 · AlphaFold monomer V2.0 prediction for DNA topoisomerase 4 subunit a (P72525) · a predicted model of the same protein · chain B against A, TM-score 0.96
Q59961 · AlphaFold monomer V2.0 prediction for DNA topoisomerase 4 subunit B (Q59961) · a predicted model of the same protein · chain D against A, TM-score 0.91

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P72525
Every structure of UniProt Q59961
Elsewhere: RCSB PDB 3FOE · PDBe 3FOE · UniProt P72525 · UniProt Q59961

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.