MolNFT v2 · #3090 · protein
Macrophage migration inhibitory factor (mif) with alanine inserted between pro-1 and met-2
1CGQ · Protein (macrophage migration inhibitory factor): “Macrophage migration inhibitory factor (mif) with alanine inserted between pro-1 and met-2”. X-ray diffraction at 2, 1 pocket (best druggability 0.82). MolNFT v2 #3090 on GenesisL1…
- PDB
- 1CGQ
- Type
- protein
- Length
- 345 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2
- Source
- Homo sapiens
- Molecule
- Protein (macrophage migration inhibitory factor)
- UniProt
- P14174
- Pockets
- 1 · best druggability 0.82
Structure
x-ray diffraction · resolution 2 · 1 distinct chain · 38% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Protein (macrophage migration inhibitory factor) | protein | 115 | 38% helix, 32% strand | P14174 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 572 | 0.82 | 0.87 | 65 | empty |
Interfaces
3 interfaces between chains.
- A–B · 1122 Ų buried · 16 hydrogen bonds · protein-protein
- A–C · 1121 Ų buried · 18 hydrogen bonds · protein-protein
- B–C · 1110 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 1CGQ · Macrophage migration inhibitory factor (mif) with alanine inserted between pro-1 and met-2 · the same entry in another collection · chain A against A, TM-score 1.00
- P14174 · AlphaFold monomer V2.0 prediction for macrophage migration inhibitory factor (P14174) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P14174
- Elsewhere: RCSB PDB 1CGQ · PDBe 1CGQ · UniProt P14174
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.