UniProt P14174
Macrophage migration inhibitory factor (P14174)
Macrophage migration inhibitory factor (UniProt P14174), EC 5.3.2.1, 5.3.3.12: 172 experimental structures on GenesisL1, 23 ligands bound, 37 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P14174
- Protein
- Macrophage migration inhibitory factor
- EC
- 5.3.2.1, 5.3.3.12
- Experimental structures
- 172
- Predicted models
- 0
- Ligands
- 23
- Pockets
- 37 · 8 records with a druggable one
Structures
172 records of P14174 in the MolNFT archive: 172 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1CA7 | Macrophage migration inhibitory factor (mif) with hydroxphenylpyruvate | x-ray diffraction | A, B, C | — | — |
| 1CA7 | Macrophage migration inhibitory factor (mif) with hydroxphenylpyruvate | x-ray diffraction | A, B, C | — | — |
| 1CGQ | Macrophage migration inhibitory factor (mif) with alanine inserted between pro-1 and met-2 | x-ray diffraction | A, B, C | — | — |
| 1CGQ | Macrophage migration inhibitory factor (mif) with alanine inserted between pro-1 and met-2 | x-ray diffraction | A, B, C | — | — |
| 1GCZ | Macrophage migration inhibitory factor (mif) complexed with inhibitor. | x-ray diffraction | A, B, C | — | — |
| 1GCZ | Macrophage migration inhibitory factor (mif) complexed with inhibitor. | x-ray diffraction | A, B, C | — | — |
| 1GD0 | Human macrophage migration inhibitory factor (mif) | x-ray diffraction | A, B, C | — | — |
| 1GD0 | Human macrophage migration inhibitory factor (mif) | x-ray diffraction | A, B, C | — | — |
| 1GIF | Human glycosylation-inhibiting factor | x-ray diffraction | A, B, C | — | — |
| 1GIF | Human glycosylation-inhibiting factor | x-ray diffraction | A, B, C | — | — |
| 1LJT | Crystal Structure of Macrophage Migration Inhibitory Factor complexed with… | x-ray diffraction | A, B, C | — | — |
| 1LJT | Crystal structure of macrophage migration inhibitory factor complexed with… | x-ray diffraction | A, B, C | — | — |
| 1MIF | Macrophage migration inhibitory factor (mif) | x-ray diffraction | A, B, C | — | — |
| 1MIF | Macrophage migration inhibitory factor (mif) | x-ray diffraction | A, B, C | — | — |
| 1P1G | Macrophage migration inhibitory factor (mif) with pro-1 mutated to gly-1 | x-ray diffraction | A, B, C | — | — |
| 1P1G | Macrophage migration inhibitory factor (mif) with pro-1 mutated to gly-1 | x-ray diffraction | A, B, C | — | — |
| 2OOH | Crystal Structure of MIF bound to a Novel Inhibitor, OXIM-11 | x-ray diffraction | A, B, C | — | — |
| 2OOH | Crystal structure of mif bound to a novel inhibitor, oxim-11 | x-ray diffraction | A, B, C | — | — |
| 2OOW | MIF Bound to a Fluorinated OXIM Derivative | x-ray diffraction | A, B, C | — | — |
| 2OOW | Mif bound to a fluorinated oxim derivative | x-ray diffraction | A, B, C | — | — |
| 2OOZ | Macrophage Migration Inhibitory Factor (MIF) Complexed with OXIM6 (an OXIM Derivative Not… | x-ray diffraction | A, B, C | — | — |
| 2OOZ | Macrophage migration inhibitory factor (mif) complexed with OXIM6 (an oxim derivative not… | x-ray diffraction | A, B, C | — | — |
| 3B9S | Macrophage Migration Inhibitory Factor (MIF) complexed with Inhibitor, 4-IPP. | x-ray diffraction | A, B, C | — | — |
| 3B9S | Macrophage migration inhibitory factor (mif) complexed with inhibitor, 4-ipp. | x-ray diffraction | A, B, C | — | — |
| 3CE4 | Structure of Macrophage Migration Inhibitory Factor Covalently Inhibited by PMSF Treatment | x-ray diffraction | A, B, C | — | — |
| 3CE4 | Structure of macrophage migration inhibitory factor covalently inhibited by pmsf treatment | x-ray diffraction | A, B, C | — | — |
| 3DJH | Macrophage Migration Inhibitory Factor (MIF) at 1.25 A Resolution | x-ray diffraction | A, B, C | — | — |
| 3DJH | Macrophage migration inhibitory factor (mif) at 1.25 a resolution | x-ray diffraction | A, B, C | — | — |
| 3DJI | Crystal Structure of Macrophage Migration Inhibitory Factor Bound to an Acetaminophen Dimer Derived… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3DJI | Crystal structure of macrophage migration inhibitory factor bound to an acetaminophen dimer derived… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3HOF | Structure of macrophage migration inhibitory factor (MIF) with caffeic acid at 1.9A resolution | x-ray diffraction | A, B, C | — | — |
| 3HOF | Structure of macrophage migration inhibitory factor (mif) with caffeic acid at 1.9A resolution | x-ray diffraction | A, B, C | — | — |
| 3IJG | Macrophage Migration Inhibitory Factor (MIF) Bound to the (R)-Stereoisomer of AV1013 | x-ray diffraction | A, B, C | — | — |
| 3IJG | Macrophage migration inhibitory factor (mif) bound to the (R)- stereoisomer of AV1013 | x-ray diffraction | A, B, C | — | — |
| 3IJJ | Ternary Complex of Macrophage Migration Inhibitory Factor (MIF) Bound Both to… | x-ray diffraction | A, B, C | — | — |
| 3IJJ | Ternary complex of macrophage migration inhibitory factor (mif) bound both to… | x-ray diffraction | A, B, C | — | — |
| 3JSF | Crystal structure of macrophage migration inhibitory factor (mif) with hydroxyquinoline inhibitor… | x-ray diffraction | A, B, C | — | — |
| 3JSF | Crystal structure of macrophage migration inhibitory factor (mif) with hydroxyquinoline inhibitor… | x-ray diffraction | A, B, C | — | — |
| 3JSG | Crystal structure of macrophage migration inhibitory factor (mif) with hydroxyquinoline inhibitor… | x-ray diffraction | A, B, C | — | — |
| 3JSG | Crystal structure of macrophage migration inhibitory factor (mif) with hydroxyquinoline inhibitor… | x-ray diffraction | A, B, C | — | — |
| 3JTU | Crystal structure of macrophage migration inhibitory factor (mif) with hydroxyquinoline inhibitor… | x-ray diffraction | A, B, C | — | — |
| 3JTU | Crystal structure of macrophage migration inhibitory factor (mif) with hydroxyquinoline inhibitor… | x-ray diffraction | A, B, C | — | — |
| 3L5P | Crystal structure of macrophage migration inhibitory factor (MIF) with imidazopyridazinol inhibitor… | x-ray diffraction | A, B, C | — | — |
| 3L5P | Crystal structure of macrophage migration inhibitory factor (mif) with imidazopyridazinol inhibitor… | x-ray diffraction | A, B, C | — | — |
| 3L5R | Crystal structure of macrophage migration inhibitory factor (MIF) with phenylchrome inhibitor at… | x-ray diffraction | A, B, C | — | — |
| 3L5R | Crystal structure of macrophage migration inhibitory factor (mif) with phenylchromenone inhibitor… | x-ray diffraction | A, B, C | — | — |
| 3L5S | Crystal structure of macrophage migration inhibitory factor (MIF) with imidazopyrimidinylphenyl… | x-ray diffraction | A, B, C | — | — |
| 3L5S | Crystal structure of macrophage migration inhibitory factor (mif) with imidazopyrimidinylphenyl… | x-ray diffraction | A, B, C | — | — |
| 3L5T | Crystal structure of macrophage migration inhibitory factor (MIF) with thiophenepiperazinylquinoli… | x-ray diffraction | A, B, C | — | — |
| 3L5T | Crystal structure of macrophage migration inhibitory factor (mif) with… | x-ray diffraction | A, B, C | — | — |
| 3L5U | Crystal structure of macrophage migration inhibitory factor (MIF) with benzothiazole inhibitor at… | x-ray diffraction | A, B, C | — | — |
| 3L5U | Crystal structure of macrophage migration inhibitory factor (mif) with benzothiazole inhibitor at… | x-ray diffraction | A, B, C | — | — |
| 3L5V | Crystal structure of macrophage migration inhibitory factor (MIF) with glycerol at 1.70A resolution | x-ray diffraction | A, B, C | — | — |
| 3L5V | Crystal structure of macrophage migration inhibitory factor (mif) with glycerol at 1.70A resolution | x-ray diffraction | A, B, C | — | — |
| 3SMB | Phenethylisothiocyanate Covalently Bound to Macrophage Migration Inhibitory Factor (MIF) | x-ray diffraction | A, B, C | — | — |
| 3SMB | Phenethylisothiocyanate covalently bound to macrophage migration inhibitory factor (mif) | x-ray diffraction | A, B, C | — | — |
| 3SMC | Macrophage Migration Inhibitory Factor (MIF) with Covalently Bound L-sulforaphane | x-ray diffraction | A, B, C | — | — |
| 3SMC | Macrophage migration inhibitory factor (mif) with covalently bound L- sulforaphane | x-ray diffraction | A, B, C | — | — |
| 3U18 | Chicago Sky Blue 6B, A Novel Inhibitor for Macrophage Migration Inhibitory Factor | x-ray diffraction | A, B, C | — | — |
| 3U18 | Chicago sky blue 6B, a novel inhibitor for macrophage migration inhibitory factor | x-ray diffraction | A, B, C | — | — |
112 records more on the page itself.
Ligands
- SO4 · Sulfate ion · in 35 records
- CL · Chloride ion · in 3 records
- C9J · 2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-7-methyl-1,7-naphthyridin-8(7H)-one · in 2 records
- EWJ · 5-(3-fluoro-1H-pyrazol-4-yl)-2-[(naphthalen-2-yl) oxy]benzoic acid · in 2 records
- 0FI · N-phenylthioformamide · in 1 record
- 30Y · (2R)-3-[(2-chlorophenyl)amino]-2-cyano-3-thioxo-N-[3-(trifluoromethyl)phenyl]propanamide · in 1 record
- 4FQ · 4-amino-5-hydroxy-6-[(E)-(3-{[3-(2-methylpropanoyl) pyrazolo[1,5-a]pyridin-2-yl]methyl}phenyl) diazenyl]naphthalene-1,3-disulfonic acid · in 1 record
- 65V · 3-({2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]quinolin-5-yl}oxy)benzoic acid · in 1 record
- 6B9 · 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-5-[(E)-(sulfanylmethylidene)amino]benzoic acid · in 1 record
- 6H1 · 6-{[4-(trifluoromethyl)phenyl]methyl}-2H-1,3-benzodioxol-5-ol · in 1 record
- 6UV · (2~{R})-2-[[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-methyl-amino]phenyl]carbonylamino]pentanedioic acid · in 1 record
- 7TN · Iguratimod · in 1 record
- C9G · 2-[1-(4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-7-methyl-1,7-naphthyridin-8(7H)-one · in 1 record
- C9Y · {2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-8-oxo-1,7-naphthyridin-7(8H)-yl}acetic acid · in 1 record
- EV7 · 2-[(naphthalen-2-yl)oxy]-5-(1H-pyrazol-4-yl)benzoic acid · in 1 record
- EWD · 2-phenoxy-5-(1H-pyrazol-4-yl)benzoic acid · in 1 record
- EWG · 3-(1H-pyrazol-4-yl)benzoic acid · in 1 record
- HWL · Flavoxate · in 1 record
- MRI · 2-[2,4-bis(oxidanyl)phenyl]-3,5,7-tris(oxidanyl) chromen-4-one · in 1 record
- MT1 · N-(4-{[(2,4-diaminopteridin-1-ium-6-yl)methyl](methyl)amino}benzoyl)-L-glutamic acid · in 1 record
- MYC · 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one · in 1 record
- NA · Sodium ion · in 1 record
- PO4 · Phosphate ion · in 1 record
Elsewhere
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