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Ligand · ZEC

ZEC · 6-hydroxy-1,3-benzothiazole-2-sulfonamide

ZEC, 6-hydroxy-1,3-benzothiazole-2-sulfonamide (C7 H6 N2 O3 S2, 230.3 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
ZEC
Formula
C7 H6 N2 O3 S2
Class
ligand
Structures
4
PDB entries
2

Binding sites

ZEC in 4 structures; the first of them:

  • 1ZFQ · carbonic anhydrase II in complex with ethoxzolamidphenole as sulfonamide inhibitor · ZEC A300 · binds GLN92, HIS94, HIS96, GLU106, HIS119, VAL121, PHE131, VAL143 and 7 more
  • 3L5U · Crystal structure of macrophage migration inhibitory factor (MIF) with benzothiazole… · ZEC A123 · binds PRO1, MET2, LYS32, TYR36, HIS62, SER63, ILE64, MET101 and 3 more
  • 1ZFQ · Carbonic anhydrase II in complex with ethoxzolamidphenole as sulfonamide inhibitor · ZEC A300 · binds GLN92, HIS94, HIS96, GLU106, HIS119, VAL121, PHE131, VAL143 and 7 more
  • 3L5U · Crystal structure of macrophage migration inhibitory factor (mif) with benzothiazole… · ZEC A123 · binds PRO1, MET2, LYS32, TYR36, HIS62, SER63, ILE64, MET101 and 3 more

Residues it binds most

HIS 10, MET 6, TYR 6, PRO 8, VAL 8, ASN 8, LYS 8, SER 8, ILE 6, TRP 4 (residue and the binding sites it lines).

Found with

  • BE7 · (4-carboxyphenyl)(chloro)mercury
  • ZN · Zinc ion
  • SO4 · Sulfate ion
  • GOL · Glycerol

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