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MolNFT v2 · #210220 · protein

Crystal structure of the Trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRT), isoform D, bound to the dead-end complex xanthine and pyrophosphate

8FWY: “Crystal structure of the Trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRT)…”. X-ray diffraction at 1.54, 2 ligands (XAN, PO4). MolNFT v2 #210220 on GenesisL1: 3D structure, binding sites and pockets…

PDB
8FWY
Type
protein
Length
431 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
1.54
Source
Trypanosoma cruzi (strain CL Brener)
UniProt
A0A7J6XZA2
Ligands
XAN, PO4

Structure

x-ray diffraction · resolution 1.54 · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein217—A0A7J6XZA2
B—protein214—A0A7J6XZA2

Ligands and binding sites

  • XAN · Xanthine · ligand · 2 copies · chains A, B
  • PO4 · Phosphate ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

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