UniProt A0A7J6XZA2
Hypoxanthine-guanine phosphoribosyltransferase (A0A7J6XZA2)
Hypoxanthine-guanine phosphoribosyltransferase (UniProt A0A7J6XZA2), EC 2.4.2.8: 3 experimental structures on GenesisL1, 4 ligands bound, 10 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A7J6XZA2
- Protein
- Hypoxanthine-guanine phosphoribosyltransferase
- EC
- 2.4.2.8
- Experimental structures
- 3
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 10 · 2 records with a druggable one
Structures
3 records of A0A7J6XZA2 in the MolNFT archive: 3 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8FWY | Crystal structure of the Trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase… | x-ray diffraction | A, B | XAN, PO4 | — |
| 8FWZ | Crystal structure of the Trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase… | x-ray diffraction | A, B | YCE, PO4 | 5 (best 0.63) |
| 8FX1 | Crystal structure of the Trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase… | x-ray diffraction | A, B | YC9 | 5 (best 0.61) |
Ligands
- PO4 · Phosphate ion · in 2 records
- XAN · Xanthine · in 1 record
- YC9 · [(3R)-4-hydroxy-3-{[(4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}butyl]phosphonic acid · in 1 record
- YCE · [(2R)-2-hydroxy-3-{[(4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}propyl]phosphonic acid · in 1 record
Elsewhere
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