GL1X · GenesisL1 explorer

MolNFT v2 · #199391 · protein + RNA

Cryo-EM structure of a yeast pre-40S ribosomal subunit - State Tsr1-2 (without Rps2)

7WTQ: “Cryo-EM structure of a yeast pre-40S ribosomal subunit - State Tsr1-2 (without Rps2)”. Electron microscopy at 3.7, 1 ligand (ZN). MolNFT v2 #199391 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7WTQ
Type
protein + RNA
Length
4,334 residues
Chains
18
Method
electron microscopy
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
3.7
Source
Saccharomyces cerevisiae
UniProt
P33442, P0CX35, P0CX37, P26786, P0CX39, O13516, P0CX47, P05756, P06367, P0C0W1, P0CX29, P0CX31, P35997, P0CX33, Q99216, P25627, Q07381
Ligands
ZN

Structure

electron microscopy · resolution 3.7 · 18 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
C2—rna1255——
SB—protein216—P33442
SE—protein260—P0CX35
SG—protein218—P0CX37
SH—protein185—P26786
SI—protein188—P0CX39
SJ—protein185—O13516
SL—protein146—P0CX47
SN—protein150—P05756
SO—protein128—P06367
SW—protein129—P0C0W1
SX—protein144—P0CX29
SY—protein134—P0CX31
Sb—protein81—P35997
Se—protein38—P0CX33
CA—protein181—Q99216
CB—protein35—P25627
CC—protein661—Q07381

Ligands and binding sites

  • ZN · Zinc ion · metal · chains Sb

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • P0C0W1 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S22-a (P0C0W1) · a predicted model of the same protein · chain SW against A, TM-score 0.98
  • P0CX39 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S8-a (P0CX39) · a predicted model of the same protein · chain SI against A, TM-score 0.98
  • P05756 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S13 (P05756) · a predicted model of the same protein · chain SN against A, TM-score 0.97
  • Q99216 · AlphaFold monomer V2.0 prediction for pre-rRNA-processing protein PNO1 (Q99216) · a predicted model of the same protein · chain CA against A, TM-score 0.97
  • P06367 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S14-a (P06367) · a predicted model of the same protein · chain SO against A, TM-score 0.95
  • P0CX31 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S24-a (P0CX31) · a predicted model of the same protein · chain SY against A, TM-score 0.95
  • P0CX47 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S11-a (P0CX47) · a predicted model of the same protein · chain SL against A, TM-score 0.94
  • P35997 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S27-a (P35997) · a predicted model of the same protein · chain Sb against A, TM-score 0.92
  • Q07381 · AlphaFold monomer V2.0 prediction for ribosome biogenesis protein TSR1 (Q07381) · a predicted model of the same protein · chain CC against A, TM-score 0.91
  • P0CX29 · AlphaFold monomer V2.0 prediction for 40S ribosomal protein S23-a (P0CX29) · a predicted model of the same protein · chain SX against A, TM-score 0.86
  • P25627 · AlphaFold monomer V2.0 prediction for 18S rRNA (GUANINE(1575)-N(7))-methyltransferase… · a predicted model of the same protein · chain CB against A, TM-score 0.72

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