MolNFT v2 · #198844 · protein
Crystal structure of serotonin 2A receptor in complex with LSD
7WC6: “Crystal structure of serotonin 2A receptor in complex with LSD”. X-ray diffraction at 2.6, 3 ligands (CLR, 7LD, MG). MolNFT v2 #198844 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7WC6
- Type
- protein
- Length
- 355 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.6
- Source
- Homo sapiens
- UniProt
- P28223
- Ligands
- CLR, 7LD, MG
Structure
x-ray diffraction · resolution 2.6 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 355 | — | P28223 |
Ligands and binding sites
- CLR · Cholesterol · ligand · chains A
- 7LD · (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide · ligand · chains A
- MG · Magnesium ion · metal · chains A
- OLC · (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate · additive · 4 copies · chains A
- PEG · Di(hydroxyethyl)ether · additive · 3 copies · chains A
- 1PE · Pentaethylene glycol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7WC6 · Crystal structure of serotonin 2A receptor in complex with lsd · the same entry in another collection · chain A against A, TM-score 1.00
- P28223 · AlphaFold monomer V2.0 prediction for 5-hydroxytryptamine receptor 2A (P28223) · a predicted model of the same protein · chain A against A, TM-score 0.86
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P28223
- Elsewhere: RCSB PDB 7WC6 · PDBe 7WC6 · UniProt P28223
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