MolNFT v2 · #195301 · protein
Structure of human PRC2-EZH1 containing phosphorylated SUZ12
7TD5: “Structure of human PRC2-EZH1 containing phosphorylated SUZ12”. X-ray diffraction at 2.994, 1 ligand (ZN). MolNFT v2 #195301 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7TD5
- Type
- protein
- Length
- 1,994 residues
- Chains
- 10
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.994
- Source
- Homo sapiens; SYNTHETIC CONSTRUCT
- UniProt
- Q92800, O75530, Q15022
- Ligands
- ZN
Structure
x-ray diffraction · resolution 2.994 · 8 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 498 | — | Q92800 |
| B | — | protein | 373 | — | O75530 |
| C, H | — | protein | 132 | — | Q15022 |
| D | — | protein | 10 | — | — |
| E, J | — | protein | 10 | — | — |
| F | — | protein | 448 | — | Q92800 |
| G | — | protein | 372 | — | O75530 |
| I | — | protein | 9 | — | — |
Ligands and binding sites
- ZN · Zinc ion · metal · 16 copies · chains A, F
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- O75530 · AlphaFold monomer V2.0 prediction for polycomb protein eed (O75530) · a predicted model of the same protein · chain G against A, TM-score 0.98
- Q92800 · AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase EZH1 (Q92800) · a predicted model of the same protein · chain F against A, TM-score 0.97
- Q15022 · AlphaFold monomer V2.0 prediction for polycomb protein SUZ12 (Q15022) · a predicted model of the same protein · chain C against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q92800
- Every structure of UniProt O75530
- Every structure of UniProt Q15022
- Elsewhere: RCSB PDB 7TD5 · PDBe 7TD5 · UniProt Q92800 · UniProt O75530 · UniProt Q15022
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