MolNFT v2 · #194812 · protein + RNA
Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 7(delta dII)
7SYM: “Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 7(delta dII)”. Electron microscopy at 4.8, 1 ligand (ZN). MolNFT v2 #194812 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7SYM
- Type
- protein + RNA
- Length
- 6,750 residues
- Chains
- 36
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 4.8
- Source
- Hepatitis C virus (isolate 1); Oryctolagus cuniculus
- UniProt
- G1TLT8, G1SS70, O18789, G1TNM3, G1TK17, G1TFM5, G1TM55, G1SVB0, G1TJW1, B7NZS8, G1TPV3, G1TRM4, G1SFR8, G1SP51, G1U472, G1U0Q2, G1SGX4, G1TU13, G1TPG3, G1TN62, G1SIZ2, G1TM82, G1TG89, G1SZ47, A0A5F9CNN4, G1TDB3, G1TZ76, G1TIB4, G1U7M4, G1T8A2, G1SK22, G1SJB4, A0A087WNH4
- Ligands
- ZN
Structure
electron microscopy · resolution 4.8 · 36 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| 2 | — | rna | 1697 | — | — |
| B | — | protein | 217 | — | G1TLT8 |
| C | — | protein | 213 | — | G1SS70 |
| D | — | protein | 221 | — | O18789 |
| E | — | protein | 228 | — | G1TNM3 |
| F | — | protein | 262 | — | G1TK17 |
| G | — | protein | 191 | — | G1TFM5 |
| H | — | protein | 237 | — | G1TM55 |
| I | — | protein | 185 | — | G1SVB0 |
| J | — | protein | 206 | — | G1TJW1 |
| K | — | protein | 185 | — | B7NZS8 |
| L | — | protein | 96 | — | G1TPV3 |
| M | — | protein | 151 | — | G1TRM4 |
| N | — | protein | 117 | — | G1SFR8 |
| O | — | protein | 149 | — | G1SP51 |
| P | — | protein | 136 | — | G1U472 |
| Q | — | protein | 115 | — | G1U0Q2 |
| R | — | protein | 142 | — | G1SGX4 |
| S | — | protein | 132 | — | G1TU13 |
| T | — | protein | 144 | — | G1TPG3 |
| U | — | protein | 141 | — | G1TN62 |
| V | — | protein | 100 | — | G1SIZ2 |
| W | — | protein | 83 | — | G1TM82 |
| X | — | protein | 129 | — | G1TG89 |
| Y | — | protein | 141 | — | G1SZ47 |
| Z | — | protein | 124 | — | A0A5F9CNN4 |
| a | — | protein | 77 | — | G1TDB3 |
| b | — | protein | 101 | — | — |
| c | — | protein | 83 | — | G1TZ76 |
| d | — | protein | 67 | — | G1TIB4 |
| e | — | protein | 55 | — | G1U7M4 |
| f | — | protein | 57 | — | G1T8A2 |
| g | — | protein | 68 | — | G1SK22 |
| h | — | protein | 313 | — | G1SJB4 |
| n | — | protein | 25 | — | A0A087WNH4 |
| z | — | rna | 162 | — | — |
Ligands and binding sites
- ZN · Zinc ion · metal · 2 copies · chains b, g
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7SYM · Structure of the HCV ires bound to the 40S ribosomal subunit, head opening. structure… · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G1TLT8
- Every structure of UniProt G1SS70
- Every structure of UniProt O18789
- Every structure of UniProt G1TNM3
- Every structure of UniProt G1TK17
- Every structure of UniProt G1TFM5
- Every structure of UniProt G1TM55
- Every structure of UniProt G1SVB0
- Every structure of UniProt G1TJW1
- Every structure of UniProt B7NZS8
- Every structure of UniProt G1TPV3
- Every structure of UniProt G1TRM4
- Every structure of UniProt G1SFR8
- Every structure of UniProt G1SP51
- Every structure of UniProt G1U472
- Every structure of UniProt G1U0Q2
- Every structure of UniProt G1SGX4
- Every structure of UniProt G1TU13
- Every structure of UniProt G1TPG3
- Every structure of UniProt G1TN62
- Every structure of UniProt G1SIZ2
- Every structure of UniProt G1TM82
- Every structure of UniProt G1TG89
- Every structure of UniProt G1SZ47
- Every structure of UniProt A0A5F9CNN4
- Every structure of UniProt G1TDB3
- Every structure of UniProt G1TZ76
- Every structure of UniProt G1TIB4
- Every structure of UniProt G1U7M4
- Every structure of UniProt G1T8A2
- Every structure of UniProt G1SK22
- Every structure of UniProt G1SJB4
- Every structure of UniProt A0A087WNH4
- Elsewhere: RCSB PDB 7SYM · PDBe 7SYM · UniProt G1TLT8 · UniProt G1SS70 · UniProt O18789 · UniProt G1TNM3 · UniProt G1TK17 · UniProt G1TFM5 · UniProt G1TM55 · UniProt G1SVB0 · UniProt G1TJW1 · UniProt B7NZS8 · UniProt G1TPV3 · UniProt G1TRM4 · UniProt G1SFR8 · UniProt G1SP51 · UniProt G1U472 · UniProt G1U0Q2 · UniProt G1SGX4 · UniProt G1TU13 · UniProt G1TPG3 · UniProt G1TN62 · UniProt G1SIZ2 · UniProt G1TM82 · UniProt G1TG89 · UniProt G1SZ47 · UniProt A0A5F9CNN4 · UniProt G1TDB3 · UniProt G1TZ76 · UniProt G1TIB4 · UniProt G1U7M4 · UniProt G1T8A2 · UniProt G1SK22 · UniProt G1SJB4 · UniProt A0A087WNH4
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