MolNFT v2 · #192733 · protein
The structure of human ABCG5/ABCG8 purified from yeast
7R89: “The structure of human ABCG5/ABCG8 purified from yeast”. Electron microscopy at 2.6, 1 ligand (ERG). MolNFT v2 #192733 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7R89
- Type
- protein
- Length
- 1,332 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.6
- Source
- Homo sapiens; Mus musculus
- UniProt
- Q9H222, Q9H221
- Ligands
- ERG
Structure
electron microscopy · resolution 2.6 · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 584 | — | Q9H222 |
| B | — | protein | 529 | — | Q9H221 |
| C | — | protein | 114 | — | — |
| D | — | protein | 105 | — | — |
Ligands and binding sites
- ERG · Ergosterol · ligand · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7R89 · The structure of human ABCG5/ABCG8 purified from yeast · the same entry in another collection · chain A against A, TM-score 1.00
- Q9H222 · AlphaFold monomer V2.0 prediction for ATP-binding cassette sub-family G member 5 (Q9H222) · a predicted model of the same protein · chain A against A, TM-score 0.99
- Q9H221 · AlphaFold monomer V2.0 prediction for ATP-binding cassette sub-family G member 8 (Q9H221) · a predicted model of the same protein · chain B against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9H222
- Every structure of UniProt Q9H221
- Elsewhere: RCSB PDB 7R89 · PDBe 7R89 · UniProt Q9H222 · UniProt Q9H221
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.